Hologenome analysis of two marine sponges with different microbiomes

BMC Genomics

Research Article

Xiaolei Wang¹  Xin Gao¹  Majed A. Alzahrani¹  Matthew Oates²  Julian Gough²  Annika Haywood³  Emily Giles³  Feras F. Lafi⁴  Manuel Aranda⁵  Sebastian Baumgarten⁵  Christian R. Voolstra⁵  Yi Jin Liew⁵  Michael L. Berumen⁵  Sylvain Foret⁶  Ute Hentschel⁷  Rachid Sougrat⁸  Celia Schunter⁹  Charalampos Mavromatis⁹  Marija Kupresanin⁹  Yanal Ghosheh⁹  Timothy Ravasi⁹  Loqmane Seridi⁹  Taewoo Ryu^1,10  Lucas Moitinho-Silva^1,11 

[1] Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Computational Bioscience Research Center, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Department of Computer Science, University of Bristol, 24 Tyndall Ave, Bristol, UK;Division of Biological and Environmental Sciences & Engineering, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Division of Biological and Environmental Sciences & Engineering, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Center for Desert Agriculture, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Division of Biological and Environmental Sciences & Engineering, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Red Sea Research Center, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Division of Evolution, Ecology and Genetics, Research School of Biology, The Australian National University, ACT 2601, Canberra, Australia;GEOMAR Helmholtz Centre for Ocean Research, RD3 Marine Microbiology and Christian-Albrechts University of Kiel, Düsternbrooker Weg 20, D-24105, Kiel, Germany;Imaging and characterization Lab, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;KAUST Environmental Epigenetic Program (KEEP), King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Division of Biological and Environmental Sciences & Engineering, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;KAUST Environmental Epigenetic Program (KEEP), King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Division of Biological and Environmental Sciences & Engineering, King Abdullah University of Science and Technology, 23955-6900, Thuwal, Kingdom of Saudi Arabia;Present address: APEC Climate Center, 48058, Busan, South Korea;School of Biotechnology and Biomolecular Sciences & Centre for Marine Bio-Innovation, University of New South Wales Sydney, Sydney, Australia;

关键词: Sponge;    Stylissa carteri;    Xestospongia testudinaria;    Innate immune system;    Host;    Microbial symbionts;    Hologenome;   

DOI  :  10.1186/s12864-016-2501-0

 received in 2015-09-27, accepted in 2016-02-18,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundSponges (Porifera) harbor distinct microbial consortia within their mesohyl interior. We herein analysed the hologenomes of Stylissa carteri and Xestospongia testudinaria, which notably differ in their microbiome content.ResultsOur analysis revealed that S. carteri has an expanded repertoire of immunological domains, specifically Scavenger Receptor Cysteine-Rich (SRCR)-like domains, compared to X. testudinaria. On the microbial side, metatranscriptome analyses revealed an overrepresentation of potential symbiosis-related domains in X. testudinaria.ConclusionsOur findings provide genomic insights into the molecular mechanisms underlying host-symbiont coevolution and may serve as a roadmap for future hologenome analyses.

【 授权许可】

CC BY   
© Ryu et al. 2016