Intraocular myofibroblastoma in an infant: a case report

BMC Ophthalmology

Case Report

Jinyong Lin¹  Shaozhen Zhao²  Ning Hua²  Xuehan Qian²  Nan Wei² 

[1] Tianjin Eye Hospital, Tianjin, China;Tianjin Medical University Eye Hospital, Tianjin, China;

关键词: Intraocular neoplasm;    Myofibroblastoma;    Infancy;   

DOI  :  10.1186/s12886-015-0082-3

 received in 2015-03-10, accepted in 2015-07-20,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundMyofibroblastoma is a benign tumor composed of spindle cells and bands of hyalinized collagen. Intraocular myofibroblastoma in infancy is rarely encountered.Case presentationThe present study reports the case of a 4-month-old female baby with intraocular myofibroblastoma. She was suspected as corneal perforation due to the rupture of a corneal neoplasm in the right eye. The anterior segment was also involved according to the Color Doppler ultrasonography. A surgical exploration was performed and the protuberant part of the mass was resected. Conventional HE staining showed numerous spindle-shaped cells with bands of collagen beneath multilayers of well-differentiated corneal epithelia. Immunohistochemical staining demonstrated the tumor cells were strong positive for vimentin and smooth muscle actin, while negative for S-100 protein. The mass was confirmed as myofibroblastoma. After 12 month follow-up, there was no apparent growth of the tumor.ConclusionsMyofibroblastoma is a very rare type of intraocular neoplasm, which may have complicated manifestation and could be misdiagnosed as dermoid or Peter’s anomaly. Histopathological and immunohistochemical staining is crucial to form a precise diagnosis.

【 授权许可】

Unknown   
© Hua et al. 2015. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.