sHSPdb: a database for the analysis of small Heat Shock Proteins

BMC Plant Biology

Database

Gilles Hunault¹  Emmanuel Jaspard² 

[1] Université d’Angers, Laboratoire d’Hémodynamique, Interaction Fibrose et Invasivité tumorale hépatique, UPRES 3859, IFR 132, F-49045, Angers, France;Université d’Angers, UMR 1345 IRHS, SFR 4207 QUASAV, Angers, France;INRA, UMR 1345 IRHS, Beaucouzé, France;Agrocampus-Ouest, UMR 1345 IRHS, Angers, France;

关键词: Small heat shock proteins;    Amino acids sequence;    Physico-chemical properties;   

DOI  :  10.1186/s12870-016-0820-6

 received in 2016-02-26, accepted in 2016-05-24,  发布年份 2016

来源: Springer

【 摘 要 】

Backgroundsmall Heat Shock Proteins (sHSP) is a wide proteins family. SHSP are found in all kingdoms and they play critical roles in plant stress tolerance mechanisms (as well as in pathogenic microorganisms and are implicated in human diseases).ResultssHSPdb (small Heat Shock Proteins database) is an integrated resource containing non-redundant, full-length and curated sequences of sHSP, classified on the basis of amino acids motifs and physico-chemical properties. sHSPdb gathers data about sHSP defined by various databases (Uniprot, PFAM, CDD, InterPro). It provides a browser interface for retrieving information from the whole database and a search interface using various criteria for retrieving a refined subset of entries. Physicochemical properties, amino acid composition and combinations are calculated for each entry. sHSPdb provides automatic statistical analysis of all sHSP properties. Among various possibilities, sHSPdb allows BLAST searches, alignment of selected sequences and submission of sequences.ConclusionssHSPdb is a new database containing information about sHSP from all kingdoms. sHSPdb provides a classification of sHSP, as well as tools and data for the analysis of the structure - function relationships of sHSP. Data are mainly related to various physico-chemical properties of the amino acids sequences of sHSP. sHSPdb is accessible at http://forge.info.univ-angers.fr/~gh/Shspdb/index.php.

【 授权许可】

CC BY   
© The Author(s). 2016