The incidence of type 1 diabetes mellitus among 15-34 years aged Lithuanian population: 18-year incidence study based on prospective databases

BMC Public Health

Research Article

Lina Radzevičienė¹  Rimantas Žalinkevičius¹  Nijolė Jurgevičienė¹  Rytas Ostrauskas¹  Lina Lašaitė¹ 

[1] Institute of Endocrinology, Lithuanian University of Health Sciences, Eiveniu 2, LT 50009, Kaunas, Lithuania;

关键词: Incidence Rate;    Insulin Therapy;    Diabetes Incidence;    Male Predominance;    Male Excess;   

DOI  :  10.1186/1471-2458-11-813

 received in 2011-07-01, accepted in 2011-10-19,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundThe aim of this prospective study was to determine the incidence of type 1 diabetes mellitus in 15-34-year-aged Lithuanian males and females during 1991 - 2008MethodsA contact system with general practitioners covering 100% of the 15-34-year-aged Lithuanian population was the primary data source. Reports from regional endocrinologists and statistical note-marks of State patient insurance fund served as secondary sources for case ascertainment.ResultsThe average age-standardized incidence rate was 8.30 per 100,000 persons per year (95% Poisson distribution confidence interval [CI] 7.90-8.71) during 1991 - 2008 and was statistically significantly higher among males (10.44 per 100,000 persons per year, 95% CI 9.82-11.10) in comparison with females (6.10 per 100,000, 95% CI 5.62-6.62). Male/female rate ratio was 1.71 (95% CI 1.63-1.80). Results of the linear 1991 - 2008 regression model showed that the incidence of Type 1 diabetes in 15-34-year-aged males and females decreased slightly over the time (r = -0.215, p > 0.05).ConclusionsOur data demonstrated the male predominance in primary incidence of type 1 diabetes mellitus in 15-34-year-aged population in Lithuania. The incidence of type 1 diabetes mellitus in 15-34-year-aged males and females decreased slightly during 1991-2008.

【 授权许可】

CC BY   
© Ostrauskas et al; licensee BioMed Central Ltd. 2011