Is gallbladder inflammation more severe in male patients presenting with acute cholecystitis?

BMC Surgery

Research Article

Dirk Wassenberg¹  Peter C Ambe²  Sebastian A Weber³ 

[1] Department of General, Visceral and thoracic surgery, St. Remigius Hospital Opladen, An St. Remigius 26, 51379, Leverkusen, Germany;Department of General, Visceral and thoracic surgery, St. Remigius Hospital Opladen, An St. Remigius 26, 51379, Leverkusen, Germany;Helios Klinikum Wuppertal, Department of Surgery II, Witten - Herdecke University, Heusner Str. 40, 42283, Wuppertal, Germany;Department of Internal Medicine, St. Elisabeth Hospital Hohenlind, Werthmannstr. 1, 50937, Köln, Germany;

关键词: Acute cholecystitis;    Laparoscopic cholecystectomy;    Male gender;    Gangrenous cholecystitis;    Necrotizing cholecystitis;   

DOI  :  10.1186/s12893-015-0034-0

 received in 2014-03-25, accepted in 2015-04-20,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundThe male gender is considered a risk factor for complications in patients undergoing laparoscopic cholecystectomy. The reasons for this gender associated risk are not clearly understood. The extent of gallbladder inflammation has been shown to influence surgical outcome. The aim of this study was to investigate whether or not gallbladder inflammation is more severe in male patients presenting with acute cholecystitis.MethodsA retrospective gender dependent comparison of the data of patients undergoing laparoscopic cholecystectomy for acute cholecystitis in a primary care facility within a five-year period was performed.Results138 patients, 69 males and 69 females were included for analysis. Severe gallbladder inflammation (gangrenous and necrotizing cholecystitis) was seen in a significant portion of the male population compared to the female population (p = 0.002). The male gender was confirmed in a multivariate analysis as an independent risk factor for severe cholecystits (p = 0.018).ConclusionThe male gender is a risk factor for severe gallbladder inflammation. An early surgical intervention may be needed to prevent complications.

【 授权许可】

CC BY   
© Ambe et al.; licensee BioMed Central. 2015