Relative lens vault in subjects with angle closure

BMC Ophthalmology

Research Article

Beong Wook Yoo¹  Hee Chan Kim²  Young Kook Kim³  Ki Ho Park⁴  Tin Aung⁵ 

[1] Bioengineering Major, Graduate School, Seoul National University, Seoul, South Korea;Department of Biomedical Engineering, College of Medicine and Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, Seoul, South Korea;Department of Ophthalmology, Jeju National University Hospital, Jeju, South Korea;Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea;Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea;Department of Ophthalmology, Singapore National Eye Center, Singapore, Singapore;

关键词: Retinal Nerve Fiber Layer;    Angle Closure;    Anterior Chamber Depth;    Glaucomatous Optic Neuropathy;    Laser Peripheral Iridotomy;   

DOI  :  10.1186/1471-2415-14-93

 received in 2014-04-29, accepted in 2014-07-16,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundThe purpose of this study was to investigate the association of a novel biometric parameter, relative lens vault (LV), with primary angle-closure (PAC) and primary angle-closure glaucoma (PACG).MethodsWe evaluated 101 subjects with PAC (G) and 101 normal subjects that were age- and gender-matched. Based on anterior-segment optical coherence tomography scans, and using customized software, the anterior vault (AV) and LV were measured. They were defined as the maximum distances between the horizontal line connecting the two scleral spurs and the posterior corneal surface and anterior lens surface, respectively. The relative LV was calculated by dividing the LV by the AV.ResultsSignificant differences between PAC (G) eyes and normal eyes were found in the LV (1.06 ± 0.41 vs. 0.36 ± 0.37 mm, P < 0.001), relative LV (0.34 ± 0.23 vs. 0.11 ± 0.25, P < 0.001), and axial length (22.96 ± 0.94 vs. 24.02 ± 1.33 mm, P < 0.001). However, the two groups’ values of the AV relative to those of axial length were quite similar (both 0.14 ± 0.03, P = 0.91). The relative LV values distinguished between PAC (G) eyes and normal eyes better than the LV values (area under the receiver operator characteristic curve: 0.97 vs. 0.92, P = 0.032).ConclusionsOur results suggest that relative dimensions of the eyeball’s anterior portion in PAC (G) eyes might be within the normal range. And the value of LV relative to that of the AV (i.e., the relative LV) is more closely related to PAC (G) than is the absolute value of LV.

【 授权许可】

Unknown   
© Kim et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.