Effect of fluoride varnish with added casein phosphopeptide-amorphous calcium phosphate on the acid resistance of the primary enamel

BMC Oral Health

Research Article

Nuray Tuloglu¹  Sule Bayrak¹  Emine Sen Tunc²  Fusun Ozer³ 

[1] Department of Pediatric Dentistry, Faculty of Dentistry, Eskisehir Osmangazi University, 26480, Eskisehir, Turkey;Department of Pediatric Dentistry, Faculty of Dentistry, Ondokuz Mayıs University, Samsun, Turkey;Department of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, USA;

关键词: Acid resistance;    CPP-ACP;    Enamel;    Fluoride;    Varnish;   

DOI  :  10.1186/s12903-016-0299-4

 received in 2016-02-16, accepted in 2016-06-07,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundThis study aimed to investigate the effects of a fluoride varnish with added Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) treatments on acid resistance of primary teeth enamel.MethodsEnamel specimens obtained from 40 primary incisors (for surface microhardness testing) and 40 primary molars (for demineralization depth measurement) were randomly divided into four groups (n = 10 incisors and 10 molars) each according to surface treatment: no treatment (control), MI varnish (1–8 % sodium fluoride and 1–5 % CPP-ACP), Clinpro White (1–5 % sodium fluoride and <5 % modified tricalcium phosphate), Duraphat (<5 % sodium fluoride). Specimens were stored for 24 h in a moist environment. After varnish residues were removed, specimens were subjected to pH cycling. The effects of fluoride varnishes were evaluated according to surface microhardness, lesion depth and structural changes. Results were analyzed by ANOVA and Tukey’s tests.ResultsThe lowest changes in surface microhardness and lesion depth occurred in MI varnish group, followed by the Clinpro White, Duraphat and no treatment (control) group (for percentage of loss surface microhardness −20.80, −34.60, −57.80 and −73.40; for lesion depth values 23.60 μm ± 3.36, 29.85 μm ± 3.27, 40.37 μm ± 3.41 and 54.56 μm ± 4.16, respectively). Statistically significant differences in both surface microhardness and lesion depth were observed among all groups (P < 0.05).ConclusionsWithin the limitations of this in vitro study, fluoride varnish containing CPP-ACP was more effective in increasing the acid resistance of primary enamel than other fluoride varnishes. However, further clinical research is needed to confirm these in vitro results.

【 授权许可】

CC BY   
© The Author(s). 2016