Antipsychotic-associated psoriatic rash – a case report

BMC Psychiatry

Case Report

Torkel Vang¹  Camelia-Eugenia Bujor²  Ole Schjerning³  Jimmi Nielsen⁴ 

[1] Department of Clinical Medicine, Aalborg University, Aalborg, Denmark;Department of Psychiatry, Aalborg University Hospital, Aalborg, Denmark;Department of Psychiatry, Aalborg University Hospital, Aalborg, Denmark;Department of Clinical Medicine, Aalborg University, Aalborg, Denmark;Department of Psychiatry, Aalborg University Hospital, Aalborg, Denmark;Department of Clinical Medicine, Aalborg University, Aalborg, Denmark;Mental Health Centre Glostrup, University of Copenhagen, Copenhagen, Denmark;

关键词: Aripiprazole;    Quetiapine;    Psoriasis;    Side effects;    Schizophrenia;    Antipsychotic drugs;    T cells;    Cytokines;   

DOI  :  10.1186/s12888-017-1411-2

 received in 2017-01-09, accepted in 2017-06-29,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundAntipsychotics are a heterogeneous group of drugs. Although, antipsychotics have been used for years, unexpected side effects may still occur. With this case report we focus on a possible association between psoriasis and antipsychotics.Data on the patient’s course of psychiatric disease, onset of psoriasis and its evolution were extracted from the patient’s medical files.Case presentationWe present a case of a 21-year-old female diagnosed with schizophrenia. She was initially treated with quetiapine, and later switched to aripiprazole due to weight gain. After initiation of antipsychotic treatment, the patient suffered from severe psoriasis lesions.ConclusionsAntipsychotics may possess immunological properties that may be involved in immune-mediated conditions, such as psoriatic rash. Further studies are warranted to determine causality and mechanism.

【 授权许可】

CC BY   
© The Author(s). 2017