Association of childhood and adult socioeconomic indicators with cardiovascular risk factors and its modification by age: the CARLA Study 2002-2006

BMC Public Health

Research Article

Karl Werdan¹  Alexander Kluttig²  Johannes Haerting²  Daniel Tiller²  Barbara Schumann³  Karin H Greiser⁴ 

[1] Department of Medicine III, Martin-Luther-University Halle-Wittenberg, 06097, Halle (Saale), Germany;Institute of Medical Epidemiology, Biostatistics, and Informatics, Martin-Luther-University Halle-Wittenberg, 06097, Halle (Saale), Germany;Institute of Medical Epidemiology, Biostatistics, and Informatics, Martin-Luther-University Halle-Wittenberg, 06097, Halle (Saale), Germany;Department of Public Health and Clinical Medicine, Epidemiology and Global Health, Umeå University, 901 87, Umeå, Sweden;Institute of Medical Epidemiology, Biostatistics, and Informatics, Martin-Luther-University Halle-Wittenberg, 06097, Halle (Saale), Germany;Division of Cancer Epidemiology, German Cancer Research Centre, 69120, Heidelberg, Germany;

关键词: Systolic Blood Pressure;    Cardiovascular Risk Factor;    Abdominal Obesity;    Educational Group;    Social Gradient;   

DOI  :  10.1186/1471-2458-11-289

 received in 2010-10-16, accepted in 2011-05-10,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundThe influence of socioeconomic status (SES) on cardiovascular diseases and risk factors is widely known, although the role of different SES indicators is not fully understood. The aim of this study was to investigate the role of different SES indicators for cardiovascular disease risk factors in a middle and old aged East German population.MethodsCross-sectional data of an East German population-based cohort study (1779 men and women aged 45 to 83) were used to assess the association of childhood and adulthood SES indicators (childhood SES, education, occupational position, income) with cardiovascular risk factors. Adjusted means and odds ratios of risk factors by SES indicators with 95% confidence intervals (CI) were calculated by linear and logistic regression models, stratified by sex. The interaction effect of education and age on cardiovascular risk factors was tested by including an interaction term.ResultsIn age-adjusted models, education, occupational position, and income were statistically significantly associated with abdominal obesity in men, and with smoking in both sexes. Men with low education had a more than threefold risk of being a smoker (OR 3.44, CI 1.58-7.51). Low childhood SES was associated with higher systolic blood pressure and abdominal obesity in women (OR 2.27, CI 1.18-4.38 for obesity); a non-significant but (in terms of effect size) relevant association of childhood SES with smoking was observed in men. In women, age was an effect modifier for education in the risk of obesity and smoking.ConclusionsWe found considerable differences in cardiovascular risk factors by education, occupational position, income, and partly by childhood social status, differing by sex. Some social inequalities levelled off in higher age. Longitudinal studies are needed to differentiate between age and birth cohort effects.

【 授权许可】

CC BY   
© Schumann et al; licensee BioMed Central Ltd. 2011