Self-perceived stress is associated with adiposity and atherosclerosis. The GEA Study

BMC Public Health

Research Article

Rosalinda Posadas-Sánchez¹  Wendy Ocampo-Arcos¹  Carlos Posadas-Romero¹  Aida Medina-Urrutia¹  Guillermo Cardoso-Saldaña¹  Janinne Ortega-Montiel¹  Esteban Jorge-Galarza¹ 

[1] Department of Endocrinology, National Institute of Cardiology “Ignacio Chavez”, Juan Badiano No. 1 Col. Seccion XVI, Tlalpan, 14080, Mexico City, Mexico;

关键词: Metabolic Syndrome;    Chronic Stress;    Psychological Stress;    Carotid Intima Media Thickness;    Carotid Atherosclerosis;   

DOI  :  10.1186/s12889-015-2112-8

 received in 2014-01-28, accepted in 2015-07-29,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundA growing body of evidence suggests that psychological stress is an independent cardiovascular risk factor. Obesity prevalence shows accelerating trends worldwide, and is known to be associated with a range of comorbidities and survival. The aim of this study was to assess the relationship between self-perceived psychological stress with parameters of adiposity, metabolic syndrome, and subclinical atherosclerosis in Mexican participants.MethodsMetabolic Syndrome was defined using the Adult Treatment Panel III criteria, obesity was defined as BMI >30, subclinical atherosclerosis disease was determined by computed tomography, and carotid intima media thickness was determined by ultrasonography. Self-perceived psychological stress was assessed using a single-item questionnaire.ResultsA total of 1243 control subjects were included in the sample, mean age 54.2 ± 9 years old; the prevalence of chronic self-perceived psychological stress (>5 years) was 10.13 %, female gender (62.7 %), obesity prevalence (48.4 %), and self-reporting sedentary lifestyle (56.3 %). The chronic stressed cohort presented higher subcutaneous abdominal fat content (285 vs 319 cm2), and carotid intima media thickness (0.63 vs 0.66 mm; p < 0.01 for both). However, after adjustment for lifestyle/social covariates (Model 1) and biological mediators (Model 2), chronic self-perceived stress was independently associated with obesity in men (OR 2.85, 95 % CI 1.51 – 5.40) and carotid atherosclerosis in women (OR 2.262, 95 % CI 1.47 – 4.67; p < 0.01 for both).ConclusionOur study suggests that self-reported chronic stress is an independent risk factor for obesity in men. In addition, carotid atherosclerosis was also found to be an independent risk factor in women in a Mexican population sample.

【 授权许可】

CC BY   
© Ortega-Montiel et al. 2015