A case report of parapneumonic pleural effusion caused by Streptococcus pneumoniae serotype 19A in a child immunized with 13-valent conjugate pneumococcal vaccine

BMC Pediatrics

Case Report

Idrissa Diawara¹  Khalid Zerouali¹  Naima Elmdaghri²  Abderrahman Abid³ 

[1] Laboratoire de Microbiologie, Faculté de Médecine et de Pharmacie, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco;Service de Microbiologie, CHU Ibn Rochd, B.P 2698, Casablanca, Morocco;Laboratoire de Microbiologie, Faculté de Médecine et de Pharmacie, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco;Service de Microbiologie, CHU Ibn Rochd, B.P 2698, Casablanca, Morocco;Institut Pasteur du Maroc, 1 Louis Pasteur place, Casablanca, Morocco;Service des Maladies Infectieuses Pédiatriques, Hôpital d’Enfants Abderrahim Harouchi, CHU Ibn Rochd, Casablanca, Morocco;

关键词: Streptococcus pneumoniae;    Serotype 19A;    Parapneumonic effusion;    Pneumococcal conjugate vaccine 13-valent;   

DOI  :  10.1186/s12887-017-0872-2

 received in 2015-09-01, accepted in 2017-04-25,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundSimple parapneumonic effusion is a pleural effusion associated with lung infection (i.e., pneumonia). Streptococcus pneumoniae remains the most common pathogen causing parapneumonic effusions. In Morocco, the pneumococcal conjugate vaccine 13-valent (PCV13) was introduced in the national immunization program in October 2010 in 2 + 1 schedule for prevention of pneumococcal disease, and replaced by the PCV10 in July 2012 in the same schedule. We report a case of parapneumonic pleural effusions caused by S. pneumoniae serotype 19A in a child immunized with 3 doses of PCV13.Case presentationThis is a 2.5 years old previously healthy Moroccan female, fully vaccinated by PCV13 and immunocompetent, admitted to a private medical clinic with a six months history of persistent asthma. On arrival (7 February 2015), she was febrile to 40.3 °C with a brutal flu syndrome, chills, dry cough and serous rhinitis, for which she received symptomatic treatment. A biological assessment was done that confirmed the clinical diagnosis of flu. Seven days after, she presented a progressive deterioration of its general condition and the onset of severe abdominal pain. She was hospitalized and a second biological assessment, computed tomography scans and chest radiography were done that confirmed a diagnosis of a pneumococcal parapneumonia with abscess of the left lower lobe with encysted empyema. Microbiological analysis of the pleural fluid showed a S. pneumoniae serotype 19A with susceptibility intermediate to penicillin. The patient was treated by antibiotics including amoxicillin, cefixime ceftriaxone and vancomycin.ConclusionsWe reported a case of parapneumonic pleural effusions caused by a vaccine serotype pneumococcal 19A occurring in an immunocompetent child immunized with 3 doses of PCV13.

【 授权许可】

CC BY   
© The Author(s). 2017