Long-term, self-reported health outcomes in kidney donors

BMC Nephrology

Research Article

Astrid Klopstad Wahl¹  Ida Torunn Bjørk²  Marit Helen Andersen³  Anders Hartmann⁴  Käthe Meyer⁴  Torbjørn Wisløff⁵ 

[1] Department of Health Sciences, Institute of Health and Society, University of Oslo, Oslo, Norway;Department of Nursing Science, Institute of Health and Society, University of Oslo, Oslo, Norway;Department of Transplantation Medicine, Division of Cancer, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Postbox 4950 Nydalen, 0424, Oslo, Norway;Department of Health Sciences, Institute of Health and Society, University of Oslo, Oslo, Norway;Department of Transplantation Medicine, Division of Cancer, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, Postbox 4950 Nydalen, 0424, Oslo, Norway;Department of Transplantation, Institute of Clinical Medicine, University of Oslo, Oslo, Norway;Oslo Centre for Biostatistics and Epidemiology, Research Support Services, Oslo University Hospital, Oslo, Norway;Department of Health Management and Health Economics, Institute of Health and Society, University of Oslo, Oslo, Norway;

关键词: Kidney donation;    Quality of life;    Fatigue;    Questionnaires;    Long term;    Health outcomes;   

DOI  :  10.1186/s12882-016-0221-y

 received in 2015-09-30, accepted in 2016-01-08,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundThe wide use of healthy persons as kidney donors calls for awareness of risks associated with donation. Live kidney donation may impair quality of life (QOL) and result in fatigue. Long-term data on these issues are generally lacking in the donor population. Thus we aimed to investigate long-term self-reported health outcomes in a nationwide donor cohort.MethodsWe assessed self-reported QOL, fatigue and psychosocial issues after donation in 217 donors representing 63 % of those who donated 8–12 years ago. QOL was measured using the generic Short Form-36 Health Survey (SF-36), fatigue using the Multidimensional Fatigue Inventory (MFI) and psychosocial issues using donor specific questions. For each of the 8 domains of SF-36 and the 5 domains of MFI, we performed generalized linear regression.ResultsDonors scored high on QOL with mean scores between 63.9 and 91.4 (scale 1–100) for the 8 subscales. Recognition from family and friends was associated with higher QOL scores in four domains. There were no significant gender differences. Fatigue scores were generally low. Females generally scored higher than males on all five dimensions of fatigue, although significantly only on two. Recipient still alive was associated with lower scores on mental fatigue. Regretting donors scored higher than average on all domains of fatigue. Recipient death, worries about own health and worsened relationship with the recipient influenced willingness to donate in retrospect. Donor age did not affect long-term health outcomes.ConclusionsEight till 12 years after donation QOL scores were generally high and improved with recogniton from family and friends. Fatigue was independent of donor age and more pronounced in females and in those who regretted donation.

【 授权许可】

CC BY   
© Meyer et al. 2016