Nutritional rehabilitation in anorexia nervosa: review of the literature and implications for treatment

BMC Psychiatry

Review

Sami A Hashim¹  Enrica Marzola²  Jennifer A Nasser³  Walter H Kaye⁴  Pei-an Betty Shih⁴ 

[1] Department of Medicine, St. Luke's/Roosevelt Hospital Center, 10025, New York, NY, USA;Department of Neuroscience, Section of Psychiatry, University of Turin, Turin, Italy;Department of Nutrition Sciences, Drexel University, 19102, Philadelphia, PA, USA;UCSD Department of Psychiatry, University of California, San Diego, 8950 Villa La Jolla Drive, Suite C – 207 La Jolla, 92037, San Diego, CA, USA;

关键词: Anorexia nervosa;    Treatment resistance;    Nutritional rehabilitation;    Refeeding;    Weight restoration;    Weight maintenance;    Caloric requirements;    Refeeding syndrome;   

DOI  :  10.1186/1471-244X-13-290

 received in 2013-04-12, accepted in 2013-08-08,  发布年份 2013

来源: Springer

【 摘 要 】

Restoration of weight and nutritional status are key elements in the treatment of anorexia nervosa (AN). This review aims to describe issues related to the caloric requirements needed to gain and maintain weight for short and long-term recovery for AN inpatients and outpatients.We reviewed the literature in PubMed pertaining to nutritional restoration in AN between 1960–2012. Based on this search, several themes emerged: 1. AN eating behavior; 2. Weight restoration in AN; 3. Role of exercise and metabolism in resistance to weight gain; 3. Medical consequences of weight restoration; 4. Rate of weight gain; 5. Weight maintenance; and 6. Nutrient intake.A fair amount is known about overall caloric requirements for weight restoration and maintenance for AN. For example, starting at 30–40 kilocalories per kilogram per day (kcal/kg/day) with increases up to 70–100 kcal/kg/day can achieve a weight gain of 1–1.5 kg/week for inpatients. However, little is known about the effects of nutritional deficits on weight gain, or how to meet nutrient requirements for restoration of nutritional status.This review seeks to draw attention to the need for the development of a foundation of basic nutritional knowledge about AN so that future treatment can be evidenced-based.

【 授权许可】

Unknown   
© Marzola et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.