What do we know about chronic kidney disease in India: first report of the Indian CKD registry

BMC Nephrology

Research Article

Sanjay K Agarwal¹  Ravi Raju Tatapudi²  Ashok L Kirpalani³  George T John⁴  Ramdas Pisharody⁵  Jai Prakash⁶  Georgi Abraham⁷  Dilip Pahari⁸  Anuradha Raman⁹  Sishir Gang^1,10  Mohan M Rajapurkar^1,10  Alan F Almeida^1,11  Vinay Sakhuja^1,12  Vivekanand Jha^1,12  RN Sahoo^1,13  Raj K Sharma^1,14  Amit Gupta^1,14  Devinder S Rana^1,15  Gopesh Modi^1,16 

[1] Department of Nephrology, All India Institute of Medical Sciences, Ansari nagar, 110029, New Delhi, India;Department of Nephrology, Andhra Medical College, M.R.Peta, 530002, Vishakhapattanam, India;Department of Nephrology, Bombay Hospital, 12, Marine Lines, 400020, Mumbai, India;Department of Nephrology, Christian Medical College, Ida Scudder Road, 632004, Vellore, India;Department of Nephrology, Government Medical College, Ulloor Road, 695011, Trivandrum, India;Department of Nephrology, Institute of Medical Sciences, Banaras Hindu University, 221005, Varanasi, India;Department of Nephrology, Madras Medical Mission, 4-A, Dr. J. Jayalalitha Nagar, Mogappair, 600037, Chennai, India;Department of Nephrology, Medica Superspecialty Hospital, 127 Mukundapur, 700099, E.M Bypass, Kolkata, India;Department of Nephrology, Mediciti Hospital, 5-9-22, Secretariat Road, 500063, Hyderabad, India;Department of Nephrology, Muljibhai Patel Society for Research in Nephro-Urology, Dr Virendra Desai Road, 387001, Nadiad, India;Department of Nephrology, P.D. Hinduja National Hospital and Medical Research Centre, Veer Savarkar Marg, 400 016, Mahim, Mumbai, India;Department of Nephrology, Postgraduate Institute of Medical Education and Research, Sector 12, 160012, Chandigarh, India;Department of Nephrology, SCB Medical College, 753007, Buxibazar, Cuttack, India;Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raibarely Road, 226014, Lucknow, India;Department of Nephrology, Sir Gangaram Hospital, Rajinder Nagar, 110060, New Delhi, India;Samarpan Kidney Center, B 288 C Sector, 462019, Shahpura, Bhopal, India;

关键词: Chronic Kidney Disease;    Diabetic Nephropathy;    Chronic Kidney Disease Patient;    Diabetic Kidney Disease;    Advanced Chronic Kidney Disease;   

DOI  :  10.1186/1471-2369-13-10

 received in 2011-07-26, accepted in 2012-03-06,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundThere are no national data on the magnitude and pattern of chronic kidney disease (CKD) in India. The Indian CKD Registry documents the demographics, etiological spectrum, practice patterns, variations and special characteristics.MethodsData was collected for this cross-sectional study in a standardized format according to predetermined criteria. Of the 52,273 adult patients, 35.5%, 27.9%, 25.6% and 11% patients came from South, North, West and East zones respectively.ResultsThe mean age was 50.1 ± 14.6 years, with M:F ratio of 70:30. Patients from North Zone were younger and those from the East Zone older. Diabetic nephropathy was the commonest cause (31%), followed by CKD of undetermined etiology (16%), chronic glomerulonephritis (14%) and hypertensive nephrosclerosis (13%). About 48% cases presented in Stage V; they were younger than those in Stages III-IV. Diabetic nephropathy patients were older, more likely to present in earlier stages of CKD and had a higher frequency of males; whereas those with CKD of unexplained etiology were younger, had more females and more frequently presented in Stage V. Patients in lower income groups had more advanced CKD at presentation. Patients presenting to public sector hospitals were poorer, younger, and more frequently had CKD of unknown etiology.ConclusionsThis report confirms the emergence of diabetic nephropathy as the pre-eminent cause in India. Patients with CKD of unknown etiology are younger, poorer and more likely to present with advanced CKD. There were some geographic variations.

【 授权许可】

Unknown   
© Rajapurkar et al; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.