Investigating the efficacy of integrated cognitive behavioral therapy for adult treatment seeking substance use disorder patients with comorbid ADHD: study protocol of a randomized controlled trial

BMC Psychiatry

Study Protocol

Maarten W Koeter¹  Wim van den Brink¹  Jack J M Dekker²  Kim de Bruijn³  Ellen Vedel³  Katelijne van Emmerik–van Oortmerssen⁴  Robert A Schoevers⁵ 

[1] Amsterdam Institute for Addiction Research, Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands;Arkin Mental Health Care and Addiction Treatment Center, Amsterdam, The Netherlands;Arkin Mental Health Care and Addiction Treatment Center, Amsterdam, The Netherlands;Jellinek Substance Abuse Treatment Center, Amsterdam, The Netherlands;Arkin Mental Health Care and Addiction Treatment Center, Amsterdam, The Netherlands;Jellinek Substance Abuse Treatment Center, Amsterdam, The Netherlands;Amsterdam Institute for Addiction Research, Department of Psychiatry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands;Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;

关键词: ADHD;    SUD;    Cognitive behavioral therapy;    Adult;    Integrated treatment;   

DOI  :  10.1186/1471-244X-13-132

 received in 2013-01-25, accepted in 2013-04-24,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundAttention deficit hyperactivity disorder (ADHD) frequently co-occurs with substance use disorders (SUD). The combination of ADHD and SUD is associated with a negative prognosis of both SUD and ADHD. Pharmacological treatments of comorbid ADHD in adult patients with SUD have not been very successful. Recent studies show positive effects of cognitive behavioral therapy (CBT) in ADHD patients without SUD, but CBT has not been studied in ADHD patients with comorbid SUD.Methods/designThis paper presents the protocol of a randomized controlled trial to test the efficacy of an integrated CBT protocol aimed at reducing SUD as well as ADHD symptoms in SUD patients with a comorbid diagnosis of ADHD. The experimental group receives 15 CBT sessions directed at symptom reduction of SUD as well as ADHD. The control group receives treatment as usual, i.e. 10 CBT sessions directed at symptom reduction of SUD only. The primary outcome is the level of self-reported ADHD symptoms. Secondary outcomes include measures of substance use, depression and anxiety, quality of life, health care consumption and neuropsychological functions.DiscussionThis is the first randomized controlled trial to test the efficacy of an integrated CBT protocol for adult SUD patients with a comorbid diagnosis of ADHD. The rationale for the trial, the design, and the strengths and limitations of the study are discussed.Trial registrationThis trial is registered in http://www.clinicaltrials.gov as NCT01431235.

【 授权许可】

CC BY   
© van Emmerik–van Oortmerssen et al.; licensee BioMed Central Ltd. 2013