Comparison of the most common isolates of postoperative endophthalmitis in South Korea; Enterococcus species vs coagulase-negative staphylococci

BMC Infectious Diseases

Research Article

Dong Park¹  Woo Jin Jeung²  Hyun Wong Kim³  Joo Eun Lee³  Ki Yup Nam⁴  Sang Joon Lee⁵  Ik Soo Byon⁶  Ji Eun Lee⁶  Jong Moon Park⁷  In Young Chung⁷  Yong Seop Han⁷  Jung Min Park⁸  Byeng Chul Yu⁹  Bu Sup Oum^1,10  Il Han Yun^1,11  Hee Sung Yoon^1,12 

[1]Crystal Eye Clinic, Busan, South Korea

[2]Department of Ophthalmology, College of Medicine, Dong-A University, Busan, South Korea

[3]Department of Ophthalmology, College of Medicine, Inje University, Busan, South Korea

[4]Department of Ophthalmology, College of Medicine, Kosin University, 262 Gamchun-ro, Seo-gu, Busan, South Korea

[5]Department of Ophthalmology, College of Medicine, Kosin University, 262 Gamchun-ro, Seo-gu, Busan, South Korea

[6]Institute for medicine, College of Medicine, Kosin University, Busan, South Korea

[7]Department of Ophthalmology, Graduate School of Medicine, Busan National University, Busan, South Korea

[8]Department of Ophthalmology, Graduate School of Medicine, Gyeongsang National University, Jinju, South Korea

[9]Department of Ophthalmology, Maryknoll Hospital, Busan, South Korea

[10]Department of Preventive Medicine, College of Medicine, Kosin University, Busan, South Korea

[11]GM St. Mary Eye Clinic, Busan, South Korea

[12]Nunevit Eye Clinic, Busan, South Korea

[13]Sungmo Eye Hospital, Busan, South Korea

关键词: Endophthalmitis;    Enterococcus faecalis;    Staphylococcus epidermidis;    Coagulase negative staphylococci;    Postoperative endophthalmitis;    Posttraumatic endophthalmitis;    Endogenous endophthalmitis;   

DOI  :  10.1186/s12879-016-2038-5

 received in 2015-11-19, accepted in 2016-11-15,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundTo compare the related factors or manifestations of the two most common isolates of post-operative endophthalmitis, which were Enterococcus spp. and coagulase-negative staphylococci (CNS) in South Korea.MethodsMedical records were reviewed for cases of post-operative endophthalmitis caused by Enterococcus spp. and CNS at eight institutions between January 2004 and July 2010. Various factors including age, sex, residence, systemic diseases, smoking and drinking history, and best corrected visual acuity, and length of time between causative intraocular surgery and symptom development were compared between the two groups.ResultsThe total number of post-operative endophthalmitis cases was 128 and in 116 cases, microbiological culture tests from the aqueous humor or vitreous were performed. Among these cases, 67 (57.8%) were culture proven. Among these 67 cases, 19 (28.4%) were caused by Enterococcus spp., 14 (20.9%) were caused by Staphylococcus epidermidis endophthalmitis, and 5 (7.5%) were caused by other CNS spp. Age, sex, causative procedure, past medical history, social history, and laterality were not different in the two groups. Mean initial and final visual acuity were significantly worse in the Enterococcus spp. endophthalmitis group than in the CNS group (p = 0.049, 0.042, respectively). Length of time between the causative procedure and symptom development was significantly shorter in cases of Enterococcus spp. endophthalmitis (p = 0.004).ConclusionsEnterococcus spp. induce more severe and rapid-onset postoperative endophthalmitis than CNS. Infectious endophthalmitis developed within 2 days after cataract operation could be caused by Enterococcus spp. and have chance to be poor prognosis in South Korea.

【 授权许可】

CC BY   
© The Author(s). 2016