Effectiveness of hygienic-dietary recommendations as enhancers of antidepressant treatment in patients with Depression: Study protocol of a randomized controlled trial

BMC Public Health

Study Protocol

Javier Garcia-Campayo¹  Margalida Gili²  Maria J Serrano²  Margalida Vives²  Saray Monzón²  Miquel Roca²  Olga Ibarra³  Joan Salva³  Mauro Garcia-Toro⁴ 

[1] Department of Psychiatry, Hospital Miguel Servet, Universidad de Zaragoza, Zaragoza, Red de Investigación en Actividades Preventivas y Promoción de la Salud (redIAPP), Spain;Institut Universitari d'Investigació en Ciències de la Salut (IUNICS), Universitat de les Illes Balears (UIB). Red de Investigación en Actividades Preventivas y Promoción de la Salud (redIAPP), Spain;Department of Psychiatry, Hospital Joan March, Palma de Mallorca, Spain;Institut Universitari d'Investigació en Ciències de la Salut (IUNICS), Universitat de les Illes Balears (UIB). Red de Investigación en Actividades Preventivas y Promoción de la Salud (redIAPP), Spain;Department of Psychiatry, Hospital Son Dureta, Palma de Mallorca, Spain;Institut Universitari d'Investigació en Ciències de la Salut (IUNICS), Universitat de les Illes Balears (UIB). Red de Investigación en Actividades Preventivas y Promoción de la Salud (redIAPP), Spain;Department of Psychiatry, Hospital Son Llatzer, Palma de Mallorca, Spain;

关键词: Major Depressive Disorder;    Sunlight Exposure;    Active Treatment Group;    Dysthymic Disorder;    Seasonal Affective Disorder;   

DOI  :  10.1186/1471-2458-10-404

 received in 2010-06-22, accepted in 2010-07-09,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundIn recent years some studies have been published supporting the efficacy of light exposure, physical activity, sleep control and a Mediterranean diet pattern on the improvement or prevention of Depression. However, to our knowledge, there have been no studies using all these measures together as an adjuvant antidepressant strategy.MethodsMulticenter, randomized, controlled, two arm-parallel, clinical trial. Eighty depressed patients undergoing standard antidepressant treatment will be advised to follow four additional hygienic-dietary recommendations about exercise, diet, sunlight exposure and sleep. Outcome measures will be assessed before and after the 6 month intervention period.DiscussionWe expect the patients in the active recommendations group to experience a greater improvement in their depressive symptoms. If so, this would be a great support for doctors who might systematically recommend these simple and costless measures, especially in primary care.Trial RegistrationISRCTN59506583

【 授权许可】

CC BY   
© Garcia-Toro et al; licensee BioMed Central Ltd. 2010