Self-reported dental hygiene, obesity, and systemic inflammation in a pediatric rural community cohort

BMC Oral Health

Research Article

Jefferson C Frisbee¹  Adam G Goodwill¹  Stephanie J Frisbee²  Richard J Crout³  Christopher B Chambers³ 

[1] Center for Cardiovascular and Respiratory Sciences, School of Medicine, West Virginia University, Morgantown, West Virginia, USA;Department of Physiology and Pharmacology, School of Medicine, West Virginia University, Morgantown, West Virginia, USA;Department of Community Medicine, School of Medicine, West Virginia University, Morgantown, West Virginia, USA;Department of Dental Practice and Rural Health, School of Dentistry, West Virginia University, Morgantown, West Virginia, USA;Center for Cardiovascular and Respiratory Sciences, School of Medicine, West Virginia University, Morgantown, West Virginia, USA;School of Dentistry, West Virginia University, Morgantown, West Virginia, USA;

关键词: Oral Health;    Systemic Inflammation;    Dental Caries;    Dental Health;    Ordinary Little Square Regression;   

DOI  :  10.1186/1472-6831-10-21

 received in 2008-12-03, accepted in 2010-09-18,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundA growing body of epidemiologic evidence links oral health, obesity, and cardiovascular health, though few studies have reported on these relationships in children. While underlying mechanisms are unclear, adult studies have suggested sub-acute systemic inflammation, also implicated in the etiology of both obesity and cardiovascular disease. This study investigated associations between self-reported dental hygiene, obesity, and systemic inflammation in children.Methods128 children < 19 years of age from rural counties in West Virginia participated in a community-based health screening that included anthropometric assessments, blood collection, and a questionnaire about dental hygiene and self-assessed oral health.ResultsParticipants ranged from 3.0-18.7 years. Univariate analysis demonstrated an association between parent-reported dental hygiene, including frequency of preventive dental care and parent-assessed overall dental health, and markers of systemic inflammation but not obesity. In multivariable regression, parent-assessed overall dental health and obesity were independent predictors of systemic inflammation, after adjustment for age, gender, and parent education.ConclusionsThis is the first known study of the association between dental hygiene, obesity, and systemic inflammation in children. These results highlight the importance of preventive dental care in overall, systemic health in children and are consistent with previous reports in adults.

【 授权许可】

CC BY   
© Frisbee et al; licensee BioMed Central Ltd. 2010