Cluster-tic syndrome as the initial manifestation of multiple sclerosis

The Journal of Headache and Pain

Brief Report

Y. Wu¹  J. Pascual¹  A. Oterino¹  C. de Pablos¹  E. de Marco¹  V. González-Quintanilla¹  M. Toriello¹ 

[1] University Hospital “Marqués de Valdecilla”, Santander, Cantabria, Spain;

关键词: Cluster Headache;    Pregabaline;    Magnetic Resonance Imaging Study;    Trigeminal Neuralgia;    Magnetic Resonance Imaging Lesion;   

DOI  :  10.1007/s10194-012-0449-2

 received in 2012-02-09, accepted in 2012-04-09,  发布年份 2012

来源: Springer

【 摘 要 】

We report the case of a patient diagnosed as having cluster-tic syndrome as the initial manifestation of multiple sclerosis (MS). The patient’s headache bouts improved after treatment with antiepileptic drugs, steroids, and beta-interferon. Magnetic resonance imaging (MRI) scans showed a pontine demyelinating lesion involving the area of the trigeminal root inlet and main sensory nucleus. Neurophysiological studies correlated well with MRI lesions. The association between cluster-tic syndrome and MS is an exception, and the mechanism of the pain is still unknown; therefore, this case might suggest a pathophysiological relationship between the trigeminal main sensory nucleus and cluster-tic syndrome.

【 授权许可】

CC BY   
© The Author(s) 2012