The validity of questionnaire-based diagnoses: the third Nord-Trøndelag Health Study 2006–2008

The Journal of Headache and Pain

Original

Grethe Helde¹  Lars Jacob Stovner²  Knut Hagen²  Kristian Bernhard Nilsen²  Geir Bråthen²  Marit Stjern²  Erling A. Tronvik²  Anne Hege Aamodt²  John-Anker Zwart³ 

[1] Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, 7489, Trondheim, Norway;Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, 7489, Trondheim, Norway;Department of Neurology and Clinical Neurophysiology, Norwegian National Headache Centre, St. Olavs University Hospital, 7006, Trondheim, Norway;Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, 7489, Trondheim, Norway;Department of Neurology, Ullevaal University Hospital, University of Oslo, 0450, Oslo, Norway;

关键词: Headache;    Migraine;    Questionnaire;    Survey;    Population;   

DOI  :  10.1007/s10194-009-0174-7

 received in 2009-09-04, accepted in 2009-11-12,  发布年份 2009

来源: Springer

【 摘 要 】

The Nord-Trøndelag Health Study (HUNT 3) performed in 2006–2008 is a replication of the cross-sectional survey from 1995 to 1997 (HUNT 2). The aim of the present study was to assess the sensitivity and specificity of questionnaire-based headache diagnoses using a personal interview by a neurologist as a gold standard. For the questionnaire-based status as headache sufferer, a sensitivity of 88%, a specificity of 86%, and a kappa statistic of 0.70 were found. Chronic headache, chronic tension-type headache (TTH), and medication overuse headache (MOH) were diagnosed with a specificity of ≥99%, and a kappa statistic of ≥0.73. Lower figures were found for the diagnoses of migraine and TTH. For individuals with headache ≥1 day per month, a sensitivity of 58% (migraine) and 96% (TTH), a specificity of 91 and 69%, and a kappa statistic of 0.54 and 0.44 were found, respectively. The specificity for migraine with aura was 95%. In conclusion, the HUNT 3-questionnaire is a valid tool for identifying headache sufferers, and diagnosing patients with chronic headache, including chronic TTH and MOH. The more moderate sensitivity for migraine and TTH makes the questionnaire-based diagnoses of migraine and TTH suboptimal for determining the prevalence. However, the high specificity of the questionnaire-based diagnosis of migraine, in particular for migraine with aura, makes the questionnaire a valid tool for diagnosing patients with migraine for genetic studies.

【 授权许可】

Unknown   
© Springer-Verlag 2009