Clinical guidelines for the prevention and treatment of osteoporosis: summary statements and recommendations from the Italian Society for Orthopaedics and Traumatology

Journal of Orthopaedics and Traumatology

Original Article

Giuseppe Toro¹  Francesca Gimigliano¹  Antimo Moretti¹  Dario Calafiore¹  Giovanni Iolascon¹  Laura Masi²  Francesca Marini²  Maria Luisa Brandi²  Luisella Cianferotti²  Gemma Marcucci²  Simone Parri²  Francesca Giusti²  Emanuela Basilici Zanetti³  Noemi Cittadini³  Rosaria Alvaro³  Eleonora Piccirilli⁴  Maurizio Feola⁴  Cecilia Rao⁴  Umberto Tarantino⁴  Giuseppina Resmini⁵ 

[1] Department of Medical and Surgical Specialties and Dentistry, Second University of Naples, Naples, Italy;Metabolic Bone Diseases Unit, Department of Surgery and Translational Medicine, University Hospital of Florence, University of Florence, Viale Pieraccini, 6, 50139, Florence, Italy;Nursing Science, Center of Excellence for Culture and Nursing Research—IPASVI, University of Rome Tor Vergata, Rome, Italy;Policlinico Tor Vergata Foundation, Orthopaedics and Traumatology, University of Rome Tor Vergata, Rome, Italy;Section of Orthopaedics and Traumatology, Centre for the Study of Osteoporosis and Metabolic Bone Disease, Treviglio-Caravaggio Hospital, Bergamo, Italy;

关键词: Fracture;    Fracture liaison service;    Guidance;    Bisphosphonates;    Denosumab;    Teriparatide;    Strontium ranelate;   

DOI  :  10.1007/s10195-017-0474-7

来源: Springer

【 摘 要 】

BackgroundThe Italian Society for Orthopaedics and Traumatology conceived this guidance—which is primarily addressed to Italian orthopedic surgeons, but should also prove useful to other bone specialists and to general practitioners—in order to improve the diagnosis, prevention, and treatment of osteoporosis and its consequences.Materials and methodsLiterature reviews by a multidisciplinary team.ResultsThe following topics are covered: the role of instrumental, metabolic, and genetic evaluations in the diagnosis of osteoporosis; appraisal of the risk of fracture and thresholds for intervention; general strategies for the prevention and treatment of osteoporosis (primary and secondary prevention); the pharmacologic treatment of osteoporosis; the setting and implementation of fracture liaison services for tertiary prevention. Grade A, B, and C recommendations are provided based on the main levels of evidence (1–3). Toolboxes for everyday clinical practice are provided.ConclusionsThe first up-to-date Italian guidelines for the primary, secondary, and tertiary prevention of osteoporosis and osteoporotic fractures are presented.

【 授权许可】

CC BY   
© The Author(s) 2017