The role of headache chronicity among predictors contributing to quality of life in patients with migraine: a hospital-based study

The Journal of Headache and Pain

Research Article

Sung-Pa Park¹  Sun-Young Kim² 

[1] Department of Neurology, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, Jung-gu, 700-842, Daegu, Republic of Korea;Department of Neurology, University of Ulsan College of Medicine, Ulsan University Hospital, 290-3 Jeonha-dong, Dong-gu, 682-714, Ulsan, Republic of Korea;

关键词: Chronic migraine;    Headache;    Disability;    Depression;    Anxiety;    Quality of life;   

DOI  :  10.1186/1129-2377-15-68

 received in 2014-07-02, accepted in 2014-08-26,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundHeadache chronicity has been known to elicit deleterious effects on quality of life (QOL). We evaluated the contribution of headache chronicity to QOL in relation to clinical, psychiatric, and psychosocial variables in patients with migraine.MethodsSubjects were recruited from a headache clinic and completed self-report questionnaires including the Migraine Disability Assessment (MIDAS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Migraine-Specific Quality of Life (MSQoL). We obtained predictors of MSQoL by multiple regression analyses. A path analysis model was constructed to analyze interrelationships between the variables.ResultsAmong 251 eligible patients, 183 (72.9%) had episodic migraine (EM) and 68 (27.1%) had chronic migraine (CM). Patients with CM had more serious clinical, psychiatric, and poor QOL than did patients with EM. The strongest predictor of the MSQoL score in all patients with migraine was the BDI score (β = -0.373, p < 0.001), followed by the MIDAS score (β = -0.223, p < 0.001), female gender (β = -0.192, p < 0.001), attack duration (β = -0.159, p = 0.001), and headache chronicity (β = -0.130, p = 0.012). Headache chronicity had a direct effect on the MSQoL score and exerted an indirect effect on the MSQoL score through the MIDAS and the BDI scores.ConclusionsChronic migraine appears to impair QOL directly as well as indirectly by provoking disability and depression.

【 授权许可】

CC BY   
© Kim and Park; licensee Springer. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.