Refining clinical features and therapeutic options of new daily persistent headache: a retrospective study of 63 patients in India

The Journal of Headache and Pain

Original

Kaushikkumar Ramanlal Rana¹  Pinaki Mahato¹  Samir Saini¹  Sanjay Prakash² 

[1] Department of Medicine, Medical College, 390001, Baroda, Gujarat, India;Department of Neurology, Medical College, SSG Hospital, O-19, Doctor’s Quarter, Jail Road, 390001, Baroda, Gujarat, India;

关键词: Headache;    New daily persistent headache;    Chronic daily headache;   

DOI  :  10.1007/s10194-012-0461-6

 received in 2012-04-09, accepted in 2012-05-08,  发布年份 2012

来源: Springer

【 摘 要 】

The aim of this retrospective study was to provide data on the clinical features and treatment outcomes of patients with NDPH (fulfilling Kung et al.’s criteria). A total of 63 patients were observed during a 5-yr period (2007–2012). More than one-third (35 %) patients had migrainous features; 65 % patients fulfilled the ICHD-II criteria. Both groups were similar in most clinical and epidemiological features. However, migrainous features were more common in patients with a prior history of episodic migraine (though statistically not significant). After a median follow-up of 9 months, 37 % patients showed “excellent” response (no or less than 1 headache per month). Another 30 % patients had “good” response (>50 % reduction in headache frequency or days per month). Excellent response was more in patients with a history of less than 6 months duration (statistically not significant). Patients with a recognized trigger showed better prognosis. Response was better in patients who received intravenous therapy of methyl prednisolone and sodium valproate. We suggest prospective and controlled studies to confirm our observations.

【 授权许可】

CC BY   
© The Author(s) 2012