Headache in juvenile myoclonic epilepsy

The Journal of Headache and Pain

Original

Veronika M. Reinisch¹  Ira Klaus¹  Christoph J. Schankin¹  Petra Sostak¹  Andreas Straube¹  Jan Rémi¹  Soheyl Noachtar¹ 

[1] Department of Neurology, University of Munich Hospital, Großhadern, Marchioninistr. 15, 81377, Munich, Germany;

关键词: Juvenile myoclonic epilepsy;    Headache;    Migraine;    Prevalence;   

DOI  :  10.1007/s10194-011-0332-6

 received in 2010-09-02, accepted in 2010-12-13,  发布年份 2011

来源: Springer

【 摘 要 】

The objective of this study was to assess the prevalence of and risk factors for primary headaches in juvenile myoclonic epilepsy (JME). Headache was classified in 75 patients with JME using a questionnaire, and its prevalence was correlated with the literature on the general population and clinical data. Headache was present in 47 patients. Thirty-one had migraine [20 migraine without aura (MO), 11 migraine with aura (MA)]. Fourteen patients with migraine had tension-type headache (TTH) in addition. Sixteen had only TTH. Comparison with the general population revealed a significantly higher prevalence of migraine (RR 4.4), MO (3.6), MA (7.3) and TTH (3.4) in JME. Risk factors for migraine and MO were female gender and for MA family history of migraine in first-degree relatives. Migraine and MA were associated with fairly controlled generalized tonic clonic seizures, MO with absences. Together with its strong genetic background, JME appears to be an attractive homogenous subtype of epilepsy for genetic research on migraine.

【 授权许可】

CC BY   
© The Author(s) 2011