Comorbidity between headache and epilepsy in a pediatric headache center

The Journal of Headache and Pain

Original

Pasquale Montagna¹  Clementina Boniver²  Francesca Menegazzo²  Pier Antonio Battistella²  Maurizio Clementi²  Leonardo Salviati²  Stefano Sartori²  Irene Toldo²  Egle Perissinotto³ 

[1] Department of Neurological Sciences, University of Bologna, Bologna, Italy;Department of Pediatrics, University of Padova, Padua, Italy;Department of Preventive Medicine and Public Health, University of Padova, Padua, Italy;

关键词: Headache;    Migraine;    Epilepsy;    Comorbidity;    Children;   

DOI  :  10.1007/s10194-010-0191-6

 received in 2009-10-16, accepted in 2010-01-12,  发布年份 2010

来源: Springer

【 摘 要 】

The purpose of this study was to analyse the comorbidity between headache and epilepsy in a large series of children with headache (1,795). Fifty-six cases (3.1%) suffered from idiopathic headache and idiopathic or cryptogenic epilepsy or unprovoked seizures. There was a strong association between migraine and epilepsy: in migraineurs (46/56) the risk of epilepsy was 3.2 times higher when compared with tension-type headache, without significant difference between migraine with and without aura (P = 0.89); children with epilepsy had a 4.5-fold increased risk of developing migraine than tension-type headache. In cases with comorbidity, focal epilepsies prevailed (43/56, 76.8%). Migraineurs affected by focal epilepsies (36/56) had a three times higher risk of having a cryptogenic epilepsy (27/36, 75%) than an idiopathic epilepsy (9/36, 25%) (P = 0.003). In migraine with aura, epilepsy preceded migraine in 71% of cases. Photosensitivity (7/56, 12.5%) and positive family history for epilepsy (22/56, 39%) were frequent in cases with comorbidity.

【 授权许可】

Unknown   
© Springer-Verlag 2010