Late onset and early onset aura: the same disorder

The Journal of Headache and Pain

Brief Report

Isabel Pavão Martins¹  Ines Mares¹  Ana Filipa Antunes²  Tomás Goucha³ 

[1] Department of Clinical Neurosciences (UNIC), Lisbon Faculty of Medicine, Instituto de Medicina Molecular (IMM), Hospital de Sta Maria, 1600, Lisbon, Portugal;GAPIC, Lisbon Faculty of Medicine, Lisbon, Portugal;Max Planck Intitute for Human Cognitive and Brain Sciences, Leipzig, Germany;

关键词: Migraine;    Migraine With Aura;    Vascular Risk Factor;    Migraine Without Aura;    Migraine Aura;   

DOI  :  10.1007/s10194-012-0419-8

 received in 2011-11-21, accepted in 2012-01-26,  发布年份 2012

来源: Springer

【 摘 要 】

Late onset aura (LOA) is usually considered benign but raises diagnostic uncertainties. We compared individuals with LOA (>45 years of age at aura onset) with those of early onset (EOA) in clinical features, vascular risk factors and imaging, in a retrospective study design including patients with migraine aura and age >44 years at first visit. In 77 cases (51 EOA and 26 LOA), no differences were found in gender distribution, family or personal history of migraine without aura, type of aura symptoms or imaging findings. LOA patients’ were more likely to not fulfil all ICHD-II aura criteria and to lack headache. This data suggest that LOA and EOA are overall identical but there are differences in presentation that deserve a better characterization by a prospective study.

【 授权许可】

CC BY   
© The Author(s) 2012