Validation of the Generalized Anxiety Disorder-7 (GAD-7) and GAD-2 in patients with migraine

The Journal of Headache and Pain

Research Article

Jong-Geun Seo¹  Sung-Pa Park¹ 

[1] Department of Neurology, School of Medicine, Kyungpook National University, 680 Gukchaebosang-ro, 700-842, Daegu, Jung-gu, Republic of Korea;

关键词: Anxiety;    Migraine;    GAD-7;    GAD-2;    Validity;   

DOI  :  10.1186/s10194-015-0583-8

 received in 2015-10-03, accepted in 2015-11-19,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundPsychiatric problems have been commonly reported in patients with migraine. This study investigated the reliability and validity of the Generalized Anxiety Disorder-7 (GAD-7) and Generalized Anxiety Disorder-2 (GAD-2) in patients with migraine.MethodsSubjects were recruited from a headache clinic and a neuropsychologist examined their GAD using the Mini International Neuropsychiatric Interview-Plus Version 5.0.0 (MINI). Subjects completed several instruments, including the GAD-7, the Beck Anxiety Inventory (BAI), the Migraine Disability Assessment Scale (MIDAS), the Headache Impact Test-6 (HIT-6), and the Migraine-Specific Quality of Life (MSQoL).ResultsAmong 146 participants, 32 patients (21.9 %) had GAD as determined by the MINI. Cronbach’s α for the GAD-7 and GAD-2 were 0.915 and 0.820, respectively. At a cutoff score of 5, the GAD-7 had a sensitivity of 78.1 %, a specificity of 74.6 %, a positive predictive value (PPV) of 46.3 %, and a negative predictive value (NPV) of 92.4 %. At a cutoff score of 1, the GAD-2 had a sensitivity of 84.4 %, a specificity of 72.8 %, a PPV of 46.6 %, and a NPV of 94.3 %. The scores of the GAD-7 and GAD-2 well correlated with the BAI score, the MIDAS score, the HIT-6 score, and the MSQoL score.ConclusionsThe GAD-7 and GAD-2 are both reliable and valid screening instruments for GAD in patients with migraine.

【 授权许可】

CC BY   
© Seo and Park. 2015