Viruses of the Turriviridae: an emerging model system for studying archaeal virus-host interactions

Frontiers in Microbiology

Microbiology

Robert D. Manuel¹  Jamie C. Snyder¹  Michael S. Overton²  C. Martin Lawrence³ 

[1] Department of Biological Sciences, Cal Poly Pomona, Pomona, CA, United States;Department of Biological Sciences, Cal Poly Pomona, Pomona, CA, United States;Division of Biological Sciences, University of California, San Diego, La Jolla, CA, United States;Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT, United States;

关键词: archaea;    virus;    Sulfolobus turreted icosahedral virus;    virus-host interaction;    viral replication;    Turriviridae;   

DOI  :  10.3389/fmicb.2023.1258997

 received in 2023-07-14, accepted in 2023-09-04,  发布年份 2023

来源: Frontiers

【 摘 要 】

Viruses have played a central role in the evolution and ecology of cellular life since it first arose. Investigations into viral molecular biology and ecological dynamics have propelled abundant progress in our understanding of living systems, including genetic inheritance, cellular signaling and trafficking, and organismal development. As well, the discovery of viral lineages that infect members of all three domains suggest that these lineages originated at the earliest stages of biological evolution. Research into these viruses is helping to elucidate the conditions under which life arose, and the dynamics that directed its early development. Archaeal viruses have only recently become a subject of intense study, but investigations have already produced intriguing and exciting results. STIV was originally discovered in Yellowstone National Park and has been the focus of concentrated research. Through this research, a viral genetic system was created, a novel lysis mechanism was discovered, and the interaction of the virus with cellular ESCRT machinery was revealed. This review will summarize the discoveries within this group of viruses and will also discuss future work.

【 授权许可】

Unknown   
Copyright © 2023 Overton, Manuel, Lawrence and Snyder.