The viewpoint of nanolipid vesicles (liposomes, exosomes, and microvesicles) as biosensors in medical health advances

Frontiers in Nanotechnology

Nanotechnology

Zahra Nasery¹  Elham Ghazizadeh² 

[1] Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Medical Biotechnology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;Department of Bioinspired Materials and Biosensor Technologies, Institute of Materials Science, Faculty of Engineering, Kiel University, Kiel, Germany;

关键词: biosensor;    lipid-based vesicle;    exosome;    liposome;    microvesicle;   

DOI  :  10.3389/fnano.2023.1230407

 received in 2023-06-08, accepted in 2023-07-25,  发布年份 2023

来源: Frontiers

【 摘 要 】

Biosensors are of significant importance today in the rapid, sensitive, and reliable detection of biological molecules in many fields, including medicine; owing to this fact, the development of a strong and reliable diagnostic agent is a very interesting topic. Because of their unique features, among other nanomaterials, lipid-based vesicles such as liposomes, exosomes, and microvesicles represent a type of biocompatible and versatile biosensing membrane surface for rapid biomarker detection and diagnosis of diseases, enhancing the assay sensitivity and decreasing the detection limit. In this review, we have reviewed the recent diagnostic application of lipid-based vesicles as biosensing substances in both conventional and novel techniques for identifying targets, especially in medicine and biotechnology sciences. Eventually, we have highlighted several recent promising developments in a new generation of biosensors based on liposome–nanomaterial hybrids and exosomes for analyzing targets and possible further advances in the future.

【 授权许可】

Unknown   
Copyright © 2023 Ghazizadeh and Nasery.