Prospective associations between hand grip strength and subsequent depressive symptoms in men and women aged 50 years and older: insights from the Survey of Health, Aging, and Retirement in Europe

Frontiers in Medicine

Medicine

Aline Schönenberg¹  Sarah Mendorf²  Tino Prell³  Konstantin G. Heimrich⁴ 

[1] Department of Geriatrics, Halle University Hospital, Halle, Germany;Department of Neurology, Jena University Hospital, Jena, Germany;Department of Neurology, Jena University Hospital, Jena, Germany;Department of Geriatrics, Halle University Hospital, Halle, Germany;Department of Neurology, Jena University Hospital, Jena, Germany;Department of Geriatrics, Jena University Hospital, Jena, Germany;

关键词: depression;    depressive symptoms;    general health;    older adults;    hand grip strength;    SHARE;   

DOI  :  10.3389/fmed.2023.1260371

 received in 2023-07-17, accepted in 2023-08-29,  发布年份 2023

来源: Frontiers

【 摘 要 】

IntroductionIn previous cross-sectional and longitudinal studies, depressive symptoms have been associated with lower hand grip strength (HGS), which is a convenient measure of overall muscular strength and serves as a marker of poor health. Most studies have considered low sample sizes or highly selective patient cohorts.MethodsWe studied the association between depressive symptoms (EURO-D) and HGS in three waves from the cross-national panel dataset Survey of Health, Aging, and Retirement in Europe (SHARE). Linear regressions and Generalized Estimating Equations (GEE) were conducted to determine factors associated with depressive symptoms and investigate whether HGS predicts future depressive symptoms.ResultsCross-sectional HGS explained 7.0% (Wave 4), 5.7% (Wave 5), and 6.4% (Wave 6) of the EURO-D variance. In the GEE, we analyzed people without depression in Wave 4 (N = 39,572). HGS predicted future EURO-D (B = −0.21, OR = 0.979, 95%CI (0.979, 0.980), p < 0.001) and remained a significant predictor of future depressive symptoms after adjustment for age, sex, psychosocial and physical covariates.DiscussionMuscle strength is a known marker for physical health, but a relation with mental health has also been proposed previously. This study confirmed the link between HGS and depressive symptoms in men and women aged ≥50 years in a large longitudinal dataset. Further research is required to understand the mechanisms behind this link to determine whether HGS can serve as a specific marker of depressive symptomology, or whether they coexist due to common underlying disease processes.

【 授权许可】

Unknown   
Copyright © 2023 Mendorf, Schönenberg, Heimrich and Prell.