Association of age-related hearing loss with cognitive impairment and dementia: an umbrella review

Frontiers in Aging Neuroscience

Aging Neuroscience

Guangran Zhao¹  Guo Ying¹  Su Su²  Xianpeng Xu³  Xin Xie⁴ 

[1] Department of Acupuncture and Moxibustion, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China;Department of Acupuncture and Moxibustion, Zhuhai Hospital of Integrated of Traditional Chinese Medicine and Western Medicine, Zhuhai, China;Department of Otolaryngology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China;Department of Rehabilitation, Heilongjiang Provincial Hospital, Harbin, China;

关键词: age-related hearing loss;    cognitive impairment;    dementia;    umbrella review;    Alzheimer’s disease;   

DOI  :  10.3389/fnagi.2023.1241224

 received in 2023-06-16, accepted in 2023-08-30,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundHearing loss, cognitive impairment and dementia have become common problems for older adults. Currently, systematic reviews and meta-analyses of the association between age-related hearing loss (ARHL) with cognitive impairment and dementia may have inconsistent results. To explore and validate the association between ARHL with cognitive impairment and dementia through summarizing and evaluating existing evidence.MethodsFrom inception to February 01, 2023, PubMed, Web of Science, Embase, and Cochrane Library databases were systematically searched. AMSTAR 2 was used to evaluate methodological quality and GRADE system was used to evaluate evidence quality. We summarized the basic characteristics of the included studies and extracted effect data for ARHL with cognitive impairment and dementia. Forest plots were used to describe the relative risk associated with ARHL and cognitive impairment, and the relative risk associated with ARHL and dementia, respectively.ResultsA total of 11 systematic reviews and meta-analyses met the inclusion criteria. Overall, the methodological quality of the included SRs/MAs was moderate and the quality of the evidence was low. The combined results found that the pooled risk ratio of ARHL and cognitive impairment was 1.30 (random-effects; 95% CI 1.16 to 1.45), and the pooled risk ratio of ARHL and dementia was 1.59 (random-effects; 95% CI 1.34 to 1.90).ConclusionBased on the evidence reported in this umbrella review, age-related hearing loss is significantly associated with cognitive impairment and dementia. Hearing loss may be a high risk factor for cognitive impairment and dementia in older adults.

【 授权许可】

Unknown   
Copyright © 2023 Ying, Zhao, Xu, Su and Xie.