Frontiers in Oncology | |
Advances in the relationship between temporal muscle thickness and prognosis of patients with glioblastoma: a narrative review | |
Oncology | |
Li Lv1  Juan Xue2  Ping Yang2  Jinhai Tang2  Xiupeng Lv2  Wanying Zhao2  Junxiu Sheng2  Qizheng Li2  Zhenghao Dong3  | |
[1] Department of Pathology, the Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China;Department of Radiation Oncology, the First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China;Department of Thoracic Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan, China; | |
关键词: glioblastoma; temporal muscle thickness; sarcopenia; frailty; prognosis; overall survival; progression-free survival; | |
DOI : 10.3389/fonc.2023.1251662 | |
received in 2023-07-02, accepted in 2023-08-28, 发布年份 2023 | |
来源: Frontiers | |
【 摘 要 】
The most dangerous variety of glioma, glioblastoma, has a high incidence and fatality rate. The prognosis for patients is still bleak despite numerous improvements in treatment approaches. We urgently need to develop clinical parameters that can evaluate patients' conditions and predict their prognosis. Various parameters are available to assess the patient's preoperative performance status and degree of frailty, but most of these parameters are subjective and therefore subject to interobserver variability. Sarcopenia can be used as an objective metric to measure a patient's physical status because studies have shown that it is linked to a bad prognosis in those with cancers. For the purpose of identifying sarcopenia, temporal muscle thickness has demonstrated to be a reliable alternative for a marker of skeletal muscle content. As a result, patients with glioblastoma may use temporal muscle thickness as a potential marker to correlate with the course and fate of their disease. This narrative review highlights and defines the viability of using temporal muscle thickness as an independent predictor of survival in glioblastoma patients, and it evaluates recent research findings on the association between temporal muscle thickness and prognosis of glioblastoma patients.
【 授权许可】
Unknown
Copyright © 2023 Tang, Dong, Sheng, Yang, Zhao, Xue, Li, Lv and Lv
【 预 览 】
Files | Size | Format | View |
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RO202310121524614ZK.pdf | 558KB | download |