Frontiers in Endocrinology | |
Multivisceral resection of nonfunctional pancreatic neuroendocrine neoplasm with nearby organ invasion: a case report | |
Endocrinology | |
Xinwei Jiang1  Lining Huang1  Cong Zhang1  Yijie Lu1  Jianwu Wu1  Song Li1  Yaopeng Xu1  Weiqiao Niu1  | |
[1] Department of Hepatobiliary Surgery, The Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School, Nanjing Medical University, Suzhou, China; | |
关键词: pancreatic neuroendocrine neoplasm; multivisceral resection; invasion; liver metastasis; debulking surgery; | |
DOI : 10.3389/fendo.2023.1236685 | |
received in 2023-06-08, accepted in 2023-09-08, 发布年份 2023 | |
来源: Frontiers | |
【 摘 要 】
Pancreatic neuroendocrine neoplasms (pNENs) are relatively rare epithelial malignancies originating from pancreatic neuroendocrine cells, pathologically classified into well-differentiated pancreatic neuroendocrine tumors (pNETs) and poorly-differentiated pancreatic neuroendocrine carcinoma (pNECs). Although they also fall under the category of pNENs, the almost entirely distinct biological characteristics and survival prognosis have caused debate among surgeons when it comes to the development of surgical intervention options, particularly for locally advanced G3 pNETs and pNECs. We present a case of 66-year-old male with nonfunctional G3 pNET, invasion of five nearby pancreatic organs and type II liver metastases. The patient achieved good outcomes after undergoing multivisceral resection and postoperative adjuvant chemotherapy. This finding helps surgeons better understand locally advanced pNENs, formulate treatment decisions systematically and confidently, and balance patient benefits and risks of surgery.
【 授权许可】
Unknown
Copyright © 2023 Zhang, Niu, Xu, Lu, Huang, Li, Jiang and Wu
【 预 览 】
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