Association between oral health and cognitive function among Chinese older adults: the Taizhou imaging study

BMC Oral Health

Research

Mei Cui¹  Haixia Lu²  Xiping Feng²  Wenjia Gu²  Fei Li²  Teck-Ek Ho²  Kelin Xu³  Jialin Li⁴  Xingdong Chen⁵  Yingzhe Wang⁶  Yanfeng Jiang⁷  Min Fan⁸ 

[1] Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China;Department of Preventive Dentistry, Shanghai Ninth People’s Hospital, College of Stomatology, National Center for Stomatology, Shanghai Key Laboratory of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, National Clinical Research Center for Oral Diseases, 639 Zhizaoju Road, 200011, Shanghai, China;Fudan University Taizhou Institute of Health Sciences, Taizhou, Jiangsu, China;Department of Biostatistics, School of Public Health, Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China;State Key Laboratory of Genetic Engineering, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai, China;State Key Laboratory of Genetic Engineering, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai, China;Fudan University Taizhou Institute of Health Sciences, Taizhou, Jiangsu, China;State Key Laboratory of Genetic Engineering, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai, China;Fudan University Taizhou Institute of Health Sciences, Taizhou, Jiangsu, China;Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China;State Key Laboratory of Genetic Engineering, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai, China;Fudan University Taizhou Institute of Health Sciences, Taizhou, Jiangsu, China;International Human Phenome Institute (Shanghai), Fudan University, 2005 Songhu Road, 200438, Shanghai, China;Taixing Disease Control and Prevention Center, Taizhou, Jiangsu, China;

关键词: Oral health;    Dental caries;    Periodontal status;    Global cognition;    Short-term memory;    Executive function;   

DOI  :  10.1186/s12903-023-03353-9

 received in 2023-02-15, accepted in 2023-08-25,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundWe aimed to investigate the association between oral health and cognitive function in a sample of older adults from a Chinese rural community.MethodsThe cross-sectional cognitive function of 677 individuals were assessed by Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). A comprehensive profile of the oral health status was evaluated by questionnaire and clinical examination.ResultsMultiple covariates-adjusted regression models demonstrated decayed teeth (DT) and decayed/missing/filled teeth (DMFT) were negatively associated with MoCA score (all p < 0.05). Calculus index (CI) and clinical attachment loss (CAL) were significantly associated with the lower MoCA, short-term memory and executive function score, respectively (all p < 0.05). Additionally, participants with missing teeth unrestored tend to get lower MMSE and MoCA scores (p < 0.05). The results also showed that increased DT and CI were modestly associated with higher odds of cognitive impairment (p < 0.05).ConclusionsThere is an association between oral health and global cognition. Poor periodontal status was strongly associated with worse global cognition performance, especially in the short-term memory and executive domain for the aging population.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

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