Antibiotic prescriptions among dentists across Norway and the impact of COVID-19 pandemic

BMC Oral Health

Research

Mohammed Al Haroni¹  Stein Atle Lie²  Farnoush Tousi³  Bodil Lund⁴ 

[1] Department of Clinical Dentistry, Faculty of Health Sciences, UiT the Arctic University of Norway, Tromsø, Norway;Centre for New Antimicrobial Strategies, UiT the Arctic University of Norway, Tromsø, Norway;Department of Clinical Dentistry, University of Bergen, Bergen, Norway;Department of Clinical Dentistry, University of Bergen, Bergen, Norway;Department of Maxillofacial Surgery, Haukeland University Hospital, Bergen, Norway;Department of Dental Medicine, Karolinska Institute, Stockholm, Sweden;Medical Unit of Plastic Surgery and Oral and Maxillofacial Surgery, Department for Oral and Maxillofacial Surgery and Jaw Orthopedics, Karolinska University Hospital, Stockholm, Sweden;

关键词: Antibiotic prescription;    Dentistry;    Dentist;    Consumption;    Defined daily doses (DDD);    COVID-19;    Phenoxymethyl penicillin;    Amoxicillin;    Metronidazole;    Clindamycin;    Amoxicillin;    Clavulanic acid;    Co-amoxiclav;   

DOI  :  10.1186/s12903-023-03380-6

 received in 2023-05-01, accepted in 2023-08-31,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundThe prescription of antibiotics in dental practice contributes significantly to the total use of antibiotics in primary healthcare. This study aimed to evaluate antibiotic prescription in dental practice during the years 2016–2021 in Norway and their relative contribution to national outpatient consumption and to investigate the influence of age, gender, geographic region, and COVID-19. A further aim was to review differences in prescribing patterns to verify effect of governmental strategies to reduce over-prescribing of antibiotics.MethodsThis register study investigated the national antibiotic prescription between 2016 and 2021. Data was obtained from the Norwegian prescription register, the Norwegian Institute of Public Health and Statistics Norway. The consumption of 12 common antibiotics was measured using WHO defined daily doses (DDDs), DDD per 1000 inhabitants per day (DIDs 1000).ResultsA total of 6,049,445 antibiotic prescriptions of the 12 investigated compounds were issued in primary care during the study period. Dentists accounted for 942,350 prescriptions corresponding to 15.6% of the total. An overall decrease in the number of prescriptions by health professions other than dentists during the 5 years (IRR = 0.92, 95% CI:0.92–0.93, p < 0.001) was observed. For dentists a slight increase in the number of prescriptions (IRR = 1.01, 95% CI: 1.01–1.01, p < 0.001) was seen over the study period. The increase of antibiotic prescriptions in dentistry was more pronounced during the COVID-19 pandemic. The 4 most prescribed type of antibiotics based on average number of DDDs of the total period 2016–2021 were in descending order; phenoxymethylpenicillin (1,109,150) followed by amoxicillin (126,244), clindamycin (72,565), and metronidazole (64,599). An unexpected finding was that the prescription of the combination compound amoxicillin/clavulanic acid had significantly increased in dentistry during the last 5 years. Geographic, gender, and age differences in the rates of prescriptions were also seen. The data revealed that there are seasonal variations in dental prescriptions.ConclusionsNoticeable differences exist in prescribing patterns of antibiotics in the last 5 years. Restricted access to dental care due to COVID-19 may have resulted in increased antibiotic prescribing in dentistry as opposed to an otherwise downward trend. Despite national guidelines there is still a need for improvement of antibiotic stewardship in dentistry and to define effective methods to disseminate information.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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