Effect of Eccentric Exercise on Metabolic Health in Diabetes and Obesity

Sports Medicine - Open

Review Article

László Török¹  Gergő Szűcs²  Márton Richárd Szabó²  Tamás Csont²  Márton Pipicz²  Csaba Csonka³ 

[1] Department of Traumatology, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis utca 6, 6720, Szeged, Hungary;Department of Sports Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Tisza Lajos krt. 107, 6720, Szeged, Hungary;Metabolic Diseases and Cell Signaling (MEDICS) Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of Szeged, Dóm tér 9, 6720, Szeged, Hungary;Centre of Excellence for Interdisciplinary Research, Development and Innovation of the University of Szeged, 6720, Szeged, Hungary;Metabolic Diseases and Cell Signaling (MEDICS) Research Group, Department of Biochemistry, Albert Szent-Györgyi Medical School, University of Szeged, Dóm tér 9, 6720, Szeged, Hungary;Centre of Excellence for Interdisciplinary Research, Development and Innovation of the University of Szeged, 6720, Szeged, Hungary;Department of Sports Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Tisza Lajos krt. 107, 6720, Szeged, Hungary;

关键词: Eccentric training;    Lengthening contraction;    Exercise;    Downhill;    Prediabetes;    Insulin resistance;    Impaired glucose tolerance;    Diabetic;    Obesity;    Overweight;    Metabolism;   

DOI  :  10.1186/s40798-023-00596-2

 received in 2022-03-28, accepted in 2023-06-12,  发布年份 2023

来源: Springer

【 摘 要 】

There is a growing body of evidence showing the importance of physical activity against civilization-induced metabolic diseases, including type 2 diabetes (T2DM) and obesity. Eccentric contraction, when skeletal muscles generate force by lengthening, is a unique type of skeletal muscle activity. Eccentric contraction may lead to better power production characteristics of the muscle because eccentric contraction requires less energy and can result in higher tension. Therefore, it is an ideal tool in the rehabilitation program of patients. However, the complex metabolic effect (i.e., fat mass reduction, increased lipid oxidation, improvement in blood lipid profile, and increased insulin sensitivity) of the eccentric contraction alone has scarcely been investigated. This paper aims to review the current literature to provide information on whether eccentric contraction can influence metabolic health and body composition in T2DM or obesity. We also discussed the potential role of myokines in mediating the effects of eccentric exercise. A better understanding of the mechanism of eccentric training and particularly their participation in the regulation of metabolic diseases may widen their possible therapeutic use and, thereby, may support the fight against the leading global risks for mortality in the world.

【 授权许可】

CC BY   
© Springer Nature Switzerland AG 2023

【 图 表 】

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