Comprehensive evaluation of functional vision, quality of life, and cognitive ability in pediatric uveitis

BMC Ophthalmology

Research

Yan Xun¹  Ying Zhu¹  Chunjiang Zhou¹  Yanlin Pu¹  Zhijun Chen¹  Guannan Su¹  Yao Wang¹  Kun Yi¹  Wenjuan Wan¹  Peizeng Yang² 

[1] The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing Eye Institute, Chongqing, P. R. China;The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Lab of Ophthalmology, Chongqing Branch of National Clinical Research Center for Ocular Diseases, Chongqing Eye Institute, Chongqing, P. R. China;The First Affiliated Hospital of Chongqing Medical University, Youyi Road 1, 400016, Chongqing, P.R. China;

关键词: Pediatric uveitis;    Visual function;    Quality of life;    Cognition;    Anxiety;    Depression.;   

DOI  :  10.1186/s12886-023-03117-7

 received in 2023-05-19, accepted in 2023-08-29,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundPediatric uveitis may cause severe impairment of vision in children and affect their quality of life as well as cognitive ability. This study aims to evaluate the functional vision, visual-related and health-related quality of life, and cognitive ability in pediatric uveitis.MethodsChildren with uveitis aged 5–16 years old completed six validated instruments to assess functional visual ability with Cardiff Visual Ability Questionnaire for Children (CVAQC), vision-related quality of life with Impact of Vision Impairment for Children (IVI-C), health-related quality of life with Pediatric Quality of Life Inventory (PedsQL), cognitive ability with Chinese Wechsler Intelligence Scale for Children (C-WISC), and depression and anxiety evaluation with Hospital Anxiety and Depression Scale (HAD).ResultsThe CVAQC, IVI-C, and PedsQL scores of pediatric uveitis were significantly lower than that of normal levels. Full-scale intelligence quotient (IQ) and performance IQ were significantly lower in pediatric uveitis patients with impaired vision in their best eye (visual acuity < 0.3) compared to those with a vision equal to or better than 0.3. Verbal IQ was significantly lower in male pediatric uveitis patients with impaired vision compared to those with a vision equal to or better than 0.3. Additionally, parents of pediatric uveitis patients with impaired vision generally had lower educational levels than parents of those with a vision equal to or better than 0.3.ConclusionsImpaired vision caused by pediatric uveitis has a significant impact on children’s functional visual ability and quality of life. The development of cognitive function in pediatric uveitis is also significantly hindered.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

Fig. 3