Well-being is associated with cortical thickness network topology of human brain

Behavioral and Brain Functions

Research

Chunlin Li¹  Lili Jiang¹  Yubin Li¹ 

[1] CAS Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, No. 16 Lincui Road, Chaoyang District, 100101, Beijing, China;Department of Psychology, University of Chinese Academy of Sciences, Shijingshan, Beijing, China;

关键词: MRI;    Well-being;    Cortical thickness;    Network efficiency;    Network centrality;   

DOI  :  10.1186/s12993-023-00219-6

 received in 2022-04-01, accepted in 2023-09-18,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundLiving a happy and meaningful life is an eternal topic in positive psychology, which is crucial for individuals’ physical and mental health as well as social functioning. Well-being can be subdivided into pleasure attainment related hedonic well-being or emotional well-being, and self-actualization related eudaimonic well-being or psychological well-being plus social well-being. Previous studies have mostly focused on human brain morphological and functional mechanisms underlying different dimensions of well-being, but no study explored brain network mechanisms of well-being, especially in terms of topological properties of human brain morphological similarity network.MethodsTherefore, in the study, we collected 65 datasets including magnetic resonance imaging (MRI) and well-being data, and constructed human brain morphological network based on morphological distribution similarity of cortical thickness to explore the correlations between topological properties including network efficiency and centrality and different dimensions of well-being.ResultsWe found emotional well-being was negatively correlated with betweenness centrality in the visual network but positively correlated with eigenvector centrality in the precentral sulcus, while the total score of well-being was positively correlated with local efficiency in the posterior cingulate cortex of cortical thickness network.ConclusionsOur findings demonstrated that different dimensions of well-being corresponded to different cortical hierarchies: hedonic well-being was involved in more preliminary cognitive processing stages including perceptual and attentional information processing, while hedonic and eudaimonic well-being might share common morphological similarity network mechanisms in the subsequent advanced cognitive processing stages.

【 授权许可】

CC BY   
© BioMed Central Ltd. 2023

【 图 表 】

Fig. 2

Fig. 1