Microleakage along the implant–abutment interface: a systematic review and meta-analysis of in vitro studies

International Journal of Implant Dentistry

Review

Franziska Schmidt¹  Andreas Schwitalla¹  Zhen Mao¹  Florian Beuer¹  Jamila Yassine¹  Qiuyan Zhu²  Daomin Wu² 

[1] Charité–Universitaetsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt- Universitaet zu Berlin, Dental Materials and Biomaterial Research, Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Aßmannshauser Str. 4-6, 14197, Berlin, Germany;Department of Oral Implantology, The Affiliated Stomatology Hospital of Kunming Medical University, Block C, No. 1088, Haiyuan Middle Road, High-Tech Zone, Kunming, Yunnan, China;

关键词: Bacterial leakage;    Implant–abutment interface;    Sealing capability;    Systematic review;    Meta-analysis;   

DOI  :  10.1186/s40729-023-00494-y

 received in 2023-03-29, accepted in 2023-08-29,  发布年份 2023

来源: Springer

【 摘 要 】

PurposeThis systematic review aimed to evaluate the incidence of microleakage events (IME) and to identify the potential factors influencing the sealing ability of the implant–abutment interface (IAI) under in vitro investigation.Material and methodsAn electronic search of MEDLINE (PubMed), EMBASE, and Web of Science databases, combined with a manual literature search was conducted up to September 2022. In vitro studies that reported the degree of microleakage at IAI under dynamic loading conditions were included. A meta-analysis was performed to calculate the mean values of the incidence of microleakage events. Subgroup analysis and meta-regression were conducted to further investigate the effect of different variables.Results675 studies were identified following the search process and 17 in vitro studies were selected according to the eligibility criteria. The weighted mean incidence of microleakage events was 47% (95% confidence interval: [0.33, 0.60]), indicating that contamination was observed in nearly half of the samples. Concerning possible factors that may influence microleakage (e.g., loading condition, assessment method, implant–abutment connection design, types of abutment material, the use of sealing agents), loading condition (p = 0.016) was the only variable that significantly influenced IME in the meta-regression analysis.ConclusionsThe results demonstrated that dynamic loading significantly increases the potential of bacterial penetration at the implant–abutment junction. The results should be interpreted carefully due to the data heterogeneity and further well-conducted in vitro studies with homogeneous samples are needed to standardize the methodologies.Graphical Abstract

【 授权许可】

CC BY   
© Deutsche Gesellschaft für Implantologie im Zahn‐, Mund‐ und Kieferbereich e.V., Japanese Society of Oral Implantology 2023

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