LncRNA SNHG1: role in tumorigenesis of multiple human cancers

Cancer Cell International

Review

Mingqiang Kang¹  Peipei Zhang¹  Huang Zeng²  Weiqiang Cai²  Shouang Zhou² 

[1] Department of Thoracic Surgery, Fujian Medical University Union Hospital, 29 Xinquan Road, 350001, Gulou, Fuzhou, China;School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China;

关键词: LncRNA;    SNHG1;    Diagnosis;    Prognosis;    Treatment;    Molecular mechanism;   

DOI  :  10.1186/s12935-023-03018-1

 received in 2023-03-22, accepted in 2023-08-06,  发布年份 2023

来源: Springer

【 摘 要 】

Small nucleolar RNA host gene 1 (SNHG1) is an important member of the SNHG family. This family is composed of a group of host genes that can be processed into small nucleolar RNAs and play important biological functions. In an oncogenic role, the SNHG1 expression is increased in various cancers, which has immense application prospects in the diagnosis, treatment, and prognosis of malignant tumors. In this review, we have summarized the role and molecular mechanism of SNHG1 in the development of various cancers. In addition, we have emphasized the clinical significance of SNHG1 in cancers in our article. This molecule is expected to be a new marker for potential usage in the diagnosis, prognosis, and treatment of cancer.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

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