Journal of Medical Case Reports | |
Solitary acrometastasis of the phalanx as initial presentation of an oligometastatic Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma: a case report | |
Case Report | |
Laura Somme1  Alexandra-Ioana Pușcașu1  Fabien Moinard-Butot1  Roland Schott1  Delphine Antoni2  | |
[1] Medical Oncology Department, Institut de Cancérologie Strasbourg Europe, 17 Rue Albert Calmette, 67200, Strasbourg, France;Radiation Oncology Department, Institut de Cancérologie Strasbourg Europe, 17 Rue Albert Calmette, 67200, Strasbourg, France; | |
关键词: Acrometastasis; Oligometastatic lung adenocarcinoma; Phalanx metastasis; | |
DOI : 10.1186/s13256-023-04127-1 | |
received in 2023-04-24, accepted in 2023-08-14, 发布年份 2023 | |
来源: Springer | |
【 摘 要 】
BackgroundAcrometastasis is an uncommon finding in non-small cell lung cancer and is usually a sign of multimetastatic disease. Few case reports have suggested solitary digital metastasis as the single secondary lesion of oligometastatic non-small cell lung cancer.Case presentationThis case report describes an unusual presentation of a Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma with a solitary bone metastasis in the fourth finger medial phalanx, which was also the first sign of the disease, in a 63-year-old Caucasian female patient. Digital surgical amputation was performed. After histopathological confirmation and radiological exclusion of other secondary lesions, chemoimmunotherapy in a first-line setting was initiated. A partial metabolic response in the primary lung lesion was observed after four cycles. Maintenance therapy is currently being continued.ConclusionSolitary digital metastasis is a rare finding in non-small cell lung cancer. Further studies are needed to investigate the mechanisms behind this particular dissemination process.
【 授权许可】
CC BY
© BioMed Central Ltd., part of Springer Nature 2023
【 预 览 】
Files | Size | Format | View |
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RO202310111212743ZK.pdf | 881KB | download | |
Fig. 6 | 572KB | Image | download |
Fig. 1 | 1252KB | Image | download |
【 图 表 】
Fig. 1
Fig. 6
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