Posterior urethral valve in thai boys

BMC Pediatrics

Research

Chompoonut Limratchapong¹  Prakorn Ekarat¹  Praewa Sophark¹  Prayong Vachvanichsanong¹  Worapat Attawettayanon² 

[1] Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, 90110, Hat Yai, Songkhla, Thailand;Department of Surgery, Faculty of Medicine, Prince of Songkla University, 90110, Hat Yai, Songkhla, Thailand;

关键词: Acute kidney injury;    Chronic kidney disease;    Hydronephrosis;    Posterior urethral valve;    Urinary tract infection;    Urinary tract obstruction;    Vesicoureteral reflux;   

DOI  :  10.1186/s12887-023-04281-x

 received in 2023-05-27, accepted in 2023-08-29,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundPosterior urethral valve (PUV) is the most common congenital bladder outlet obstruction in boys, causing renal damage beginning in utero. There are scarce data from Thailand regarding the long-term outcomes of PUV in boys, thus the aim of this study was to examine the presentation, clinical course, complications, outcomes and renal survival in PUV boys.MethodsWe reviewed the medical records of PUV boys treated at the Pediatric Nephrology Clinic, Prince of Songkla University, Thailand, over a 30-year-period.ResultsSeventy-seven PUV boys were identified, with a median age at diagnosis of 4.8 months. The most common presentations were urinary tract infection (UTI), poor urine stream and urinary dribbling in 26 (33.8%), 19 (24.7%) and 11 (14.3%) boys, respectively. Renal ultrasound results in 70 boys showed 8 (11.4%) unilateral and 56 (80%) bilateral hydronephroses. Of 72 voiding cystourethrograms, 18 (25.0%) showed unilateral and 22 (30.6%) bilateral vesicoureteral refluxes. 99mTc dimercaptosuccinic acid renal scans in 30 boys showed 12 (40%) unilateral and 8 (26.7%) bilateral renal damage. Fifty-nine (76.6%) boys had 149 UTIs; 42 (54.4%) had recurrent UTI. Forty-eight boys had valve ablation at the median age of 30.3 months. 22 boys (28.6%) developed chronic kidney disease (CKD) at a median age of 15.0 years.ConclusionOf 77 PUV Thai boys, UTI was the most common presentation. Recurrence of UTI and CKD was the most common consequence. Lifelong follow-up for renal and bladder functions is essential for all PUV patients.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

【 图 表 】

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Fig. 7