The value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs

Frontiers in Medicine

Medicine

Jianping Xu¹  Tianzhuo Yu¹  Lin Zhang¹  Xiulei Yu¹  Jun Meng¹  Ying Zhang² 

[1] Department of Ultrasonography, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Zhejiang Integrated Traditional and Western Medicine Hospital, Hangzhou Red Cross Hospital, Hangzhou, China;null;

关键词: multimodal ultrasound;    tuberculous lymphadenitis;    contrast-enhanced ultrasound;    anti-tuberculosis treatment;    cevical;   

DOI  :  10.3389/fmed.2023.1177045

 received in 2023-03-01, accepted in 2023-07-05,  发布年份 2023

来源: Frontiers

【 摘 要 】

PurposeIn order to research the value of multimodal ultrasonography in evaluating therapeutic response of cervical tuberculous lymphadenitis to anti-tuberculosis drugs.Materials and methodsSixty-one patients with cervical tuberculous lymphadenitis were enrolled in this study. Ultrasound examination was performed before systemic standard anti-tuberculosis treatment and within 1–2 months after treatment, and the patients were divided into effective group and ineffective group according to the follow-up at the sixth month. The multimodal ultrasound signs of the two groups were compared and analyzed.ResultsIn the effective group, there were significant differences in the maximum diameter of lymph nodes, the echo of the surrounding tissue and the enlargement of the contrast area before and after treatment (p < 0.05). At 1–2 months after treatment, there were significant differences in the maximum diameter, pus changes, CDFI, elasticity scores, echo of surrounding tissues, changes in enlarged and non-enhanced areas after contrast enhancement between the effective group and the ineffective group (p < 0.05).ConclusionThe multimodal ultrasound signs of the appearance of internal pus or non-enhancement area enlargement, enhanced echo of the surrounding tissue and enlargement after CEUS are related to poor prognosis, and may be used to evaluate the response of anti-tuberculosis chemotherapy when the size change of lymph node is not obvious in individual treatment.

【 授权许可】

Unknown   
Copyright © 2023 Yu, Zhang, Xu, Meng, Yu and Zhang.