Advances in gut microbiome in metabonomics perspective: based on bibliometrics methods and visualization analysis

Frontiers in Cellular and Infection Microbiology

Cellular and Infection Microbiology

Peng Dong¹  Jieyan Wang²  Hui Liang²  Yantong Wan³  Jianan Ding⁴  Shuqian Zheng⁴  Liugang Tang⁵  Pinfei Pan⁶  Yiyin Mai⁷ 

[1] College of Anesthesiology, Southern Medical University, Guangzhou, China;The First School of Clinical Medicine, Southern Medical University, Guangzhou, China;Department of Urology, The People's Hospital of Longhua, The Affiliated Hospital of Southern Medical University, Shenzen, China;Guangdong Provincial Key Laboratory of Proteomics, Southern Medical University, Guangzhou, China;School of Basic Medical Science, Southern Medical University, Guangzhou, China;Tendon and Injury Department, Sichuan Provincial Orthopedics Hospital, Chengdu, China;The First School of Clinical Medicine, Southern Medical University, Guangzhou, China;The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China;

关键词: gut microbiome;    metabonomics;    bibliometrics;    cluster analysis;    visualization analysis;   

DOI  :  10.3389/fcimb.2023.1196967

 received in 2023-04-04, accepted in 2023-05-09,  发布年份 2023

来源: Frontiers

【 摘 要 】

Background and aimsGastrointestinal microbial metabolomics is closely related to the state of the organism and has significant interaction with the pathogenesis of many diseases. Based on the publications in Web of Science Core Collection(WoSCC) from 2004 to 2022, this study conducted a bibliometric analysis of this field, aiming to understand its development trend and frontier, and provide basic information and potential points for in-depth exploration of this field.MethodsAll articles on gastrointestinal flora and metabolism published from 2004 to 2022 were collected and identified in WoCSS. CiteSpace v.6.1 and VOSviewer v.1.6.15.0 were used to calculate bibliometric indicators, including number of publications and citations, study categories, countries/institutions, authors/co-cited authors, journals/co-cited journals, co-cited references, and keywords. A map was drawn to visualize the data based on the analysis results for a more intuitive view.ResultsThere were 3811 articles in WoSCC that met our criteria. Analysis results show that the number of publications and citations in this field are increasing year by year. China is the country with the highest number of publications and USA owns the highest total link strength and citations. Chinese Acad Sci rank first for the number of institutional publications and total link strength. Journal of Proteome Research has the most publications. Nicholson, Jeremy K. is one of the most important scholars in this field. The most cited reference is “Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease”. Burst detection indicates that Urine, spectroscopy, metabonomic and gut microflora are long-standing hot topics in this field, while autism spectrum disorder and omics are likely to be at the forefront of research. The study of related metabolic small molecules and the application of gastrointestinal microbiome metabolomics in various diseases are currently emerging research directions and frontier in this field.ConclusionThis study is the first to make a bibliometric analysis of the studies related to gastrointestinal microbial metabolomics and reveal the development trends and current research hotspots in this field. This can contribute to the development of the field by providing relevant scholars with valuable and effective information about the current state of the field.

【 授权许可】

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Copyright © 2023 Wang, Dong, Zheng, Mai, Ding, Pan, Tang, Wan and Liang