Editorial: The role of posttranslational modifications in polyglutamine diseases

Frontiers in Molecular Neuroscience

Molecular Neuroscience

Huu Phuc Nguyen¹  Jonasz Jeremiasz Weber²  K. Matthew Scaglione³  Maria do Carmo Costa⁴  Sokol V. Todi⁵ 

[1] Department of Human Genetics, Ruhr University Bochum, Bochum, Germany;Department of Human Genetics, Ruhr University Bochum, Bochum, Germany;Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany;Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, United States;Department of Neurology, Michigan Medicine, University of Michigan, Ann Arbor, MI, United States;Department of Pharmacology, Wayne State University, Detroit, MI, United States;

关键词: Huntington's disease;    spinobulbar muscular atrophy;    spinocerebellar ataxia;    phosphorylation;    protein aggregation;    protein clearance;    protein fragmentation;    ubiquitination;   

DOI  :  10.3389/fnmol.2023.1271226

 received in 2023-08-01, accepted in 2023-08-02,  发布年份 2023

来源: Frontiers

【 授权许可】

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Copyright © 2023 Weber, Costa, Scaglione, Todi and Nguyen.