Frontiers in Physiology | |
Toxicity of microplastics and nanoplastics: invisible killers of female fertility and offspring health | |
Physiology | |
Zhuo Zhang1 Xiaohu Xu2 Xiao Wu2 Haoxu Dong2 Wenwen Ma2 Kunkun Song2 Yanjing Huang3 Fan Li3 Runan Hu3 Zhuo Liu3 Yuli Geng3 Yufan Song4 | |
[1] Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;Department of Traditional Chinese Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;Department of Traditional Chinese Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; | |
关键词: microplastics; nanoplastics; reproductive toxicity; cross-generational; environmental toxicants; | |
DOI : 10.3389/fphys.2023.1254886 | |
received in 2023-07-10, accepted in 2023-08-16, 发布年份 2023 | |
来源: Frontiers | |
【 摘 要 】
Microplastics (MPs) and nanoplastics (NPs) are emergent pollutants, which have sparked widespread concern. They can infiltrate the body via ingestion, inhalation, and cutaneous contact. As such, there is a general worry that MPs/NPs may have an impact on human health in addition to the environmental issues they engender. The threat of MPs/NPs to the liver, gastrointestinal system, and inflammatory levels have been thoroughly documented in the previous research. With the detection of MPs/NPs in fetal compartment and the prevalence of infertility, an increasing number of studies have put an emphasis on their reproductive toxicity in female. Moreover, MPs/NPs have the potential to interact with other contaminants, thus enhancing or diminishing the combined toxicity. This review summarizes the deleterious effects of MPs/NPs and co-exposure with other pollutants on female throughout the reproduction period of various species, spanning from reproductive failure to cross-generational developmental disorders in progenies. Although these impacts may not be directly extrapolated to humans, they do provide a framework for evaluating the potential mechanisms underlying the reproductive toxicity of MPs/NPs.
【 授权许可】
Unknown
Copyright © 2023 Geng, Liu, Hu, Huang, Li, Ma, Wu, Dong, Song, Xu, Zhang and Song.
【 预 览 】
Files | Size | Format | View |
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RO202310109183348ZK.pdf | 1558KB | download |