An fMRI study of finger movements in children with and without dyslexia

Frontiers in Neuroscience

Neuroscience

Ted K. Turesky¹  Megan M. Luetje¹  Guinevere F. Eden² 

[1] Center for the Study of Learning, Georgetown University Medical Center, Washington, DC, United States;null;

关键词: connectivity;    dyslexia;    finger;    motor;    reading;    reading disability;   

DOI  :  10.3389/fnins.2023.1135437

 received in 2022-12-31, accepted in 2023-04-24,  发布年份 2023

来源: Frontiers

【 摘 要 】

IntroductionDevelopmental dyslexia is a language-based reading disability, yet some have reported motor impairments, usually attributed to cerebellar dysfunction.MethodsUsing fMRI, we compared children with and without dyslexia during irregularly paced, left or right-hand finger tapping. Next, we examined seed-to-voxel intrinsic functional connectivity (iFC) using six seed regions of the motor system (left and right anterior lobe of the cerebellum, SM1 and SMA).ResultsA whole-brain task-evoked analysis revealed relatively less activation in the group with dyslexia in right anterior cerebellum during right hand tapping. For iFC, we found the group with dyslexia to have greater iFC between the right SM1 seed and a medial aspect of right postcentral gyrus for left hand tapping; and greater iFC between the left SM1 seed and left thalamus, as well as weaker local iFC around the left SM1 seed region for right hand tapping. Lastly, extracted activity and connectivity values that had been identified in these between-group comparisons were not correlated with measures of reading.DiscussionWe conclude that there are some aberrations in motor system function in children with dyslexia, but these are not tied to reading ability.

【 授权许可】

Unknown   
Copyright © 2023 Turesky, Luetje and Eden.