Time discrimination and change detection could share a common brain network: findings of a task-based fMRI study

Frontiers in Psychology

Psychology

María Sol Garcés¹  Felipe Ortuño²  Irene Alústiza²  Patricio Molero²  Cristina Vidal-Adroher²  Javier Goena³  Miguel Fernández⁴  Reyes García-Eulate⁵  María Fernández-Seara⁵ 

[1] Department of Psychiatry and Clinical Psychology, Clínica Universidad de Navarra, Pamplona, Spain;Colegio de Ciencias Sociales y Humanidades, Universidad San Francisco de Quito, Quito, Ecuador;Instituto de Neurociencias, Universidad San Francisco de Quito, Quito, Ecuador;Department of Psychiatry and Clinical Psychology, Clínica Universidad de Navarra, Pamplona, Spain;Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain;Department of Psychiatry and Clinical Psychology, Clínica Universidad de Navarra, Pamplona, Spain;Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain;Department of Psychiatry, Basurto University Hospital, Bilbao, Spain;Department of Radiology, Clínica Universidad de Navarra, Pamplona, Spain;Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain;Department of Radiology, Clínica Universidad de Navarra, Pamplona, Spain;

关键词: time discrimination;    time perception;    change detection;    oddball paradigm;    salience;    cognition;    cognitive control;    fMRI;   

DOI  :  10.3389/fpsyg.2023.1110972

 received in 2022-11-29, accepted in 2023-06-05,  发布年份 2023

来源: Frontiers

【 摘 要 】

IntroductionOver the past few years, several studies have described the brain activation pattern related to both time discrimination (TD) and change detection processes. We hypothesize that both processes share a common brain network which may play a significant role in more complex cognitive processes. The main goal of this proof-of-concept study is to describe the pattern of brain activity involved in TD and oddball detection (OD) paradigms, and in processes requiring higher cognitive effort.MethodsWe designed an experimental task, including an auditory test tool to assess TD and OD paradigms, which was conducted under functional magnetic resonance imaging (fMRI) in 14 healthy participants. We added a cognitive control component into both paradigms in our test tool. We used the general linear model (GLM) to analyze the individual fMRI data images and the random effects model for group inference.ResultsWe defined the areas of brain activation related to TD and OD paradigms. We performed a conjunction analysis of contrast TD (task > control) and OD (task > control) patterns, finding both similarities and significant differences between them.DiscussionWe conclude that change detection and other cognitive processes requiring an increase in cognitive effort require participation of overlapping functional and neuroanatomical components, suggesting the presence of a common time and change detection network. This is of particular relevance for future research on normal cognitive functioning in the healthy population, as well as for the study of cognitive impairment and clinical manifestations associated with various neuropsychiatric conditions such as schizophrenia.

【 授权许可】

Unknown   
Copyright © 2023 Goena, Alústiza, Vidal-Adroher, Garcés, Fernández, Molero, García-Eulate, Fernández-Seara and Ortuño.