Investigating suicidality across the autistic-catatonic continuum in a clinical sample of subjects with major depressive disorder and borderline personality disorder

Frontiers in Psychiatry

Psychiatry

Marianna De Gregorio¹  Antonino Reitano¹  Maria Rosaria Anna Muscatello¹  Natascia Brondino²  Pierluigi Politi²  Marta Nola²  Francesca Benedetti³  Simone Battaglini³  Benedetta Nardi³  Ivan Mirko Cremone³  Claudia Carmassi³  Davide Gravina³  Liliana Dell’Osso³  Gabriele Massimetti³  Barbara Carpita³  Chiara Bonelli³  Giulia Amatori³  Giacomo Deste⁴  Antonio Vita⁴  Maurizio Pompili⁵  Isabella Berardelli⁵  Mario Luciano⁶  Mario Maj⁶ 

[1] Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy;Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy;Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy;Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy;Department of Neuroscience, Mental Health and Sense Organs, University of Roma “La Sapienza”, Rome, Italy;Department of Psychiatry, University of Campania “Luigi Vanvitelli”, Naples, Italy;

关键词: catatonia spectrum;    mood disorder;    major depression disorder (MDD);    borderline personality disorder (BPD);    suicide;    catatonic traits;    catatonia;    autistic-catatonic continuum;   

DOI  :  10.3389/fpsyt.2023.1124241

 received in 2022-12-14, accepted in 2023-05-04,  发布年份 2023

来源: Frontiers

【 摘 要 】

BackgroundRecent literature has highlighted that catatonia may be more prevalent among psychiatric patients than previously thought, beginning from autism spectrum disorders (ASD), for which it has been suggested to represent a severe late consequence, but also among individuals with mood disorders and borderline personality disorder (BPD). Interestingly, one critical point shared by these conditions is the increased risk of suicidality. The aim of this study was to evaluate how the presence and the prevalence of catatonic symptoms may shape and correlate with suicidal risk in a sample of individuals with major depressive disorder (MDD) or BPD.MethodsWe recruited two clinical samples of subjects (BPD and MDD) and a control group without a diagnosis according to DSM-5 (CTL). Subjects were assessed with the catatonia spectrum (CS) and the MOODS-SR for evaluating suicidality.ResultsIn the total sample, suicidality score was significantly and positively correlated with all CS domains and CS total score. Correlation and regression analyses highlighted specific patterns of association among Catatonia spectrum domains and suicidality in the MDD and BPD group and in the total sample.ConclusionIn both disorders, higher catatonic traits are linked to higher suicidal tendencies, confirming the high risk of suicide for this population. However, different patterns of association between catatonic symptoms and suicidality were highlighted in the two disorders.

【 授权许可】

Unknown   
Copyright © 2023 Dell’Osso, Nardi, Bonelli, Gravina, Benedetti, Amatori, Battaglini, Massimetti, Luciano, Berardelli, Brondino, De Gregorio, Deste, Nola, Reitano, Muscatello, Pompili, Politi, Vita, Carmassi, Cremone, Carpita and Maj.