Case Report: Early detection of lung carcinoid in an asymptomatic individual by blood-test initiated PET-CT imaging

Frontiers in Oncology

Oncology

Martin Gosau¹  Simon Burg¹  Ralf Smeets²  Audrey Laure Céline Grust²  Katja Failing³ 

[1] Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany;Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany;Department of Oral and Maxillofacial Surgery, Division of “Regenerative Orofacial Medicine”, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany;Precura Center, Darmstadt, Germany;

关键词: early cancer screening;    Apo10/DNaseX;    TKTL1;    immunological biopsy;    blood test;    FDG-PET/CT;   

DOI  :  10.3389/fonc.2023.1177237

 received in 2023-03-01, accepted in 2023-05-19,  发布年份 2023

来源: Frontiers

【 摘 要 】

We present the case of a 53-year-old woman who was diagnosed with early-stage lung cancer by targeted cancer screening consisting of an immunological biopsy-based blood test followed by radiological imaging. The PanTum Detect blood test detects the biomarkers Apo10/DNaseX and Transketolase-like 1 (TKTL1) in circulating macrophage-like cells from peripheral blood samples to identify asymptomatic individuals with a high risk for malignancy. The elevated blood test values initiated an 18F-FDG PET/CT visualization for further clarification. In this case, imaging indicated a lung carcinoma in the right upper lobe. A biopsy confirmed the presence of a lung carcinoma, which was removed surgically. Histologic examination revealed a typical I A2 carcinoid, which was completely removed, making further therapy obsolete.

【 授权许可】

Unknown   
Copyright © 2023 Burg, Smeets, Gosau, Failing and Grust